日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Paenitracins, a novel family of bacitracin-type nonribosomal peptide antibiotics produced by plant-associated Paenibacillus species

类杆菌肽(Paenitracins)是一类新型的杆菌肽类非核糖体肽抗生素,由植物相关类杆菌属(Paenibacillus)产生。

Machushynets, Nataliia V; Elsayed, Somayah S; Du, Chao; Lysenko, Vladyslav; de la Cruz, Mercedes; Sanchez, Pilar; Genilloud, Olga; Martin, Nathaniel I; Liles, Mark R; van Wezel, Gilles P

Structure-Activity Studies on the Antitubercular Natural Product Evybactin

抗结核天然产物依维巴克汀的构效关系研究

Lysenko, Vladyslav; Theriault, Monique E; Sterk, Fabienne A C; Choudhari, Parth; Son, Sangkeun; Lewis, Kim; Martin, Nathaniel I

Experimental glycopeptide antibiotic EVG7 prevents recurrent Clostridioides difficile infection by sparing members of the Lachnospiraceae family

实验性糖肽类抗生素EVG7通过保护毛螺菌科成员来预防艰难梭菌的复发性感染。

Mons, Elma; Henderickx, Jannie G E; Sanders, Ingrid M J G; Rader, Anusca G; Perkins, Caroline E; Stel, Florence M; van Groesen, Emma; Smits, Wiep Klaas; Theriot, Casey M; Martin, Nathaniel I

Chemical diversification of polyprenyl quinones for mechanistic studies on menaquinone-binding peptide antibiotics

聚异戊二烯基醌的化学多样化及其在甲萘醌结合肽类抗生素机制研究中的应用

Matheson, Eilidh J; van Beekveld, Roy A M; Innocenti, Paolo; Martin, Nathaniel I; Weingarth, Markus; Cochrane, Stephen A

The novel GlcNAc 6-phosphate dehydratase NagS governs a metabolic checkpoint that controls nutrient signaling in Streptomyces

新型 GlcNAc 6-磷酸脱水酶 NagS 调控链霉菌中的代谢检查点,该检查点控制营养信号传导。

Li, Chao; Urem, Mia; Kotsogianni, Ioli; Lau, Josephine; Du, Chao; Elsayed, Somayah S; Martin, Nathaniel I; McNae, Iain W; Voskamp, Patrick; Mayer, Christoph; Rigali, Sébastien; Pannu, Navraj; Abrahams, Jan Pieter; Schada von Borzyskowski, Lennart; van Wezel, Gilles P

Exploring the Chemical Space of Paenibacillus NRPs and Discovery of Paenilipoheptin B

探索类芽孢杆菌非核糖体蛋白的化学空间并发现类芽孢杆菌脂肽B

Machushynets, Nataliia V; Lysenko, Vladyslav; Du, Chao; Slingerland, Cornelis J; Elsayed, Somayah S; Liles, Mark R; Martin, Nathaniel I; van Wezel, Gilles P

Total Synthesis, Structure Elucidation, and Bioactivity Evaluation of the Cyclic Lipopeptide Natural Product Paenilipoheptin A

环状脂肽天然产物帕尼利波肽A的全合成、结构解析及生物活性评价

Lysenko, Vladyslav; Machushynets, Nataliia V; van Dam, Jisca L; Sterk, Fabienne A C; Speer, Alexander; Ram, Arthur F J; Slingerland, Cornelis J; Van Wezel, Gilles P; Martin, Nathaniel I

Small Molecule Inhibitors of Nicotinamide N-Methyltransferase Enzyme for the Treatment of Osteosarcoma and Merkel Cell Carcinoma: Potential for the Development of a Targeted Therapeutic Strategy

烟酰胺N-甲基转移酶小分子抑制剂治疗骨肉瘤和默克尔细胞癌:靶向治疗策略的开发潜力

Pompei, Veronica; Cecati, Monia; Serritelli, Emma Nicol; Gerini, Eleonora; Campagna, Roberto; Pozzi, Valentina; Van Haren, Matthijs J; Martin, Nathaniel I; Emanuelli, Monica; Sartini, Davide

Design, Synthesis, and Antibacterial Evaluation of Rifampicin-Siderophore Conjugates

利福平-铁载体缀合物的设计、合成及抗菌活性评价

Lysenko, Vladyslav; Gao, Mei-Ling; Sterk, Fabienne A C; Innocenti, Paolo; Slingerland, Cornelis J; Martin, Nathaniel I

An Rcs Stress-Based High-Throughput Screen Reveals Novel Gyrase Inhibitors as Indirect Inducers of Cell Envelope Stress in Gram-Negative Bacteria

基于RCS应激的高通量筛选揭示新型DNA促旋酶抑制剂作为革兰氏阴性细菌细胞包膜应激的间接诱导剂

Cleenewerk, Laurence; Otto, Alexandra; Wouters, Willemijn; Willemse, Joost; Gao, Meiling; Lysenko, Vladyslav; Punt, Jeroen M; van der Stelt, Mario; Martin, Nathaniel I; van Ulsen, Peter; Luirink, Joen