日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Detection of host cell microprotein impurities in antibody drug products

抗体药物产品中宿主细胞微生物蛋白杂质的检测

Ioanna Tzani #, Marina Castro-Rivadeneyra #, Paul Kelly, Lisa Strasser, Lin Zhang, Martin Clynes, Barry L Karger, Niall Barron, Jonathan Bones #, Colin Clarke #

miRNA- and Cell Line-Specific Constraints on Precursor miRNA Processing of Stably Transfected Pancreatic Cancer and Other Mammalian Cells

miRNA 和细胞系特异性限制对稳定转染的胰腺癌和其他哺乳动物细胞的前体 miRNA 加工

Taylor J Allen-Coyle, Berta Capella Roca, Alan Costello, Niall Barron, Joanne Keenan, Martin Clynes, Fiona O'Neill, Finbarr O'Sullivan

Alteration in Levels of Specific miRNAs and Their Potential Protein Targets between Human Pancreatic Cancer Samples, Adjacent Normal Tissue, and Xenografts Derived from These Tumors

人类胰腺癌样本、邻近正常组织和源自这些肿瘤的异种移植瘤之间特定 miRNA 及其潜在蛋白质靶标水平的变化

Fiona O'Neill, Taylor-Jade Allen-Coyle, Sandra Roche, Justine Meiller, Neil T Conlon, Niall Swan, Robert M Straubinger, Justin Geoghegan, Ninfa L Straubinger, Kevin Conlon, Ray McDermott, Finbarr O'Sullivan, Michael Henry, Paula Meleady, Gerard McVey, Robert O'Connor, Michael Moriarty, Martin Clynes

Differential expression of miRNAs and functional role of mir-200a in high and low productivity CHO cells expressing an Fc fusion protein

表达 Fc 融合蛋白的高产和低产 CHO 细胞中 miRNA 的差异表达和 mir-200a 的功能作用

Laura Bryan, Michael Henry, Niall Barron, Clair Gallagher, Ronan M Kelly, Christopher C Frye, Matthew D Osborne, Martin Clynes, Paula Meleady

Copper toxicity of inflection point in human intestinal cell line Caco-2 dissected: influence of temporal expression patterns

人类肠道细胞系 Caco-2 拐点铜毒性解剖:时间表达模式的影响

Joanne Keenan, Paula Meleady, Charles O'Doherty, Michael Henry, Martin Clynes, Karina Horgan, Richard Murphy, Finbarr O'Sullivan

Altered gene expression in CHO cells following polyamine starvation

多胺饥饿后 CHO 细胞基因表达发生改变

Berta Capella Roca, Padraig Doolan, Niall Barron, Fiona O'Neill, Martin Clynes

Establishment and Characterisation by Expression Microarray of Patient-Derived Xenograft Panel of Human Pancreatic Adenocarcinoma Patients

人类胰腺腺癌患者异种移植瘤表达微阵列的建立及鉴定

Sandra Roche, Fiona O'Neill, Jean Murphy, Niall Swan, Justine Meiller, Neil T Conlon, Justin Geoghegan, Kevin Conlon, Ray McDermott, Rozana Rahman, Sinead Toomey, Ninfa L Straubinger, Robert M Straubinger, Robert O'Connor, Gerard McVey, Michael Moriarty, Martin Clynes

Genomic Profiling and Functional Analysis of let-7c miRNA-mRNA Interactions Identify SOX13 to Be Involved in Invasion and Progression of Pancreatic Cancer

let-7c miRNA-mRNA 相互作用的基因组分析和功能分析表明 SOX13 参与胰腺癌的侵袭和进展

Shannon R Nelson, Sandra Roche, Maura Cotter, Pablo Anton Garcia, Daniela Reitmeier, Elisabeth Zollbrecht, Fiona O'Neill, Martin Clynes, Padraig Doolan, Jai P Medha, Niall Swan, AnneMarie Larkin, Naomi Walsh

Continuous translation of circularized mRNA improves recombinant protein titer

环化 mRNA 的持续翻译可提高重组蛋白的滴度

Alan Costello, Nga T Lao, Niall Barron, Martin Clynes

An arginase-based system for selection of transfected CHO cells without the use of toxic chemicals

基于精氨酸酶的系统,用于筛选转染的 CHO 细胞,无需使用有毒化学物质

Berta Capella Roca, Nga Lao, Niall Barron, Padraig Doolan, Martin Clynes