日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Palbociclib and dsRNA sensor co-operate to enhance anti-cancer effects through ER stress and modulation of immune evasion

Palbociclib 和 dsRNA 传感器协同作用，通过内质网应激和调节免疫逃逸来增强抗癌作用。

期刊:Nature Communications
影响因子:14.7
doi:10.1038/s41467-025-60133-5
Victoria Roulstone # ，Joan Kyula-Currie # ，James Wright ，Emmanuel C Patin ，Isaac Dean ，Lu Yu ，Aida Barreiro-Alonso ，Miriam Melake ，Jyoti Choudhary ，Richard Elliott ，Christopher J Lord ，David Mansfield ，Nik Matthews ，Ritika Chauhan ，Victoria Jennings ，Charleen Chan Wah Hak ，Holly Baldock ，Francesca Butera ，Elizabeth Appleton ，Pablo Nenclares ，Malin Pedersen ，Shane Foo ，Amarin Wongariyapak ，Antonio Rullan ，Tencho Tenev ，Pascal Meier ，Richard Vile ，Hardev Pandha ，Alan Melcher ，Martin McLaughlin ，Kevin J Harrington
免疫/内分泌
肿瘤
BOC
ALB
肿瘤免疫
发表日期：2025
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Sculpting the tumour microenvironment by combining radiotherapy and ATR inhibition for curative-intent adjuvant immunotherapy

通过放射治疗和 ATR 抑制相结合来塑造肿瘤微环境，以实现治愈性辅助免疫治疗

期刊:Nature Communications
影响因子:14.7
doi:10.1038/s41467-024-51236-6
Emmanuel C Patin, Pablo Nenclares, Charleen Chan Wah Hak, Magnus T Dillon, Anton Patrikeev, Martin McLaughlin, Lorna Grove, Shane Foo, Heba Soliman, Joao P Barata, Joanna Marsden, Holly Baldock, Jim Gkantalis, Victoria Roulstone, Joan Kyula, Amy Burley, Lisa Hubbard, Malin Pedersen, Simon A Smith, E
肿瘤
发表日期：2024
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Combination of oncolytic Maraba virus with immune checkpoint blockade overcomes therapy resistance in an immunologically cold model of advanced melanoma with dysfunctional T-cell receptor signalling

溶瘤马拉巴病毒与免疫检查点阻断相结合，克服了 T 细胞受体信号传导功能障碍的晚期黑色素瘤免疫冷模型中的治疗耐药性

期刊:Journal for ImmunoTherapy of Cancer
影响因子:10.3
doi:10.1136/jitc-2024-009443
Edward Armstrong, Matthew K L Chiu, Shane Foo, Lizzie Appleton, Pablo Nenclares, Anton Patrikeev, Nitya Mohan, Martin Mclaughlin, Galabina Bozhanova, Julia Hoebart, Victoria Roulstone, Emmanuel Patin, Malin Pedersen, Joan Kyula, Masahiro Ono, Fiona Errington-Mais, John Bell, Kevin J Harrington, Alan
信号转导
微生物学
肿瘤
黑色素瘤
T细胞
Checkpoint
T Cell Receptor
发表日期：2024
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Antitumour effect of the mitochondrial complex III inhibitor Atovaquone in combination with anti-PD-L1 therapy in mouse cancer models

线粒体复合物 III 抑制剂阿托伐醌联合抗 PD-L1 疗法对小鼠癌症模型的抗肿瘤作用

期刊:Cell Death & Disease
影响因子:8.1
doi:10.1038/s41419-023-06405-8
Gonzalo Rodriguez-Berriguete, Rathi Puliyadi, Nicole Machado, Alessandro Barberis, Remko Prevo, Martin McLaughlin, Francesca M Buffa, Kevin J Harrington, Geoff S Higgins
肿瘤
AROS
发表日期：2024
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CD4 T cell dynamics shape the immune response to combination oncolytic herpes virus and BRAF inhibitor therapy for melanoma

CD4 T 细胞动力学影响溶瘤疱疹病毒和 BRAF 抑制剂联合治疗黑色素瘤的免疫反应

期刊:Journal for ImmunoTherapy of Cancer
影响因子:10.3
doi:10.1136/jitc-2021-004410
Galabina Bozhanova, Jehanne Hassan, Lizzie Appleton, Victoria Jennings, Shane Foo, Martin McLaughlin, Charleen Ml Chan Wah Hak, Emmanuel C Patin, Eva Crespo-Rodriguez, Gabby Baker, Edward Armstrong, Matthew Chiu, Hardev Pandha, Adel Samson, Victoria Roulstone, Joan Kyula, Richard Vile, Fiona Erringt
免疫
微生物学
疱疹
黑色素瘤
T细胞
发表日期：2022
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Oculomotor corollary discharge signaling is related to repetitive behavior in children with autism spectrum disorder

眼动伴随放电信号与自闭症谱系障碍儿童的重复行为有关

期刊:Journal of Vision
影响因子:2.3
doi:10.1167/jov.21.8.9
Yao, Beier; Rolfs, Martin; McLaughlin, Christopher; Isenstein, Emily L; Guillory, Sylvia B; Grosman, Hannah; Kashy, Deborah A; Foss-Feig, Jennifer H; Thakkar, Katharine N
信号转导
自闭症
神经科学
发表日期：2021
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Shortwave infrared polymethine fluorophores matched to excitation lasers enable non-invasive, multicolour in vivo imaging in real time

短波红外聚甲炔荧光染料与激发激光器匹配，可实现非侵入式、多色实时体内成像。

期刊:Nature Chemistry
影响因子:20.2
doi:10.1038/s41557-020-00554-5
Cosco, Emily D; Spearman, Anthony L; Ramakrishnan, Shyam; Lingg, Jakob G P; Saccomano, Mara; Pengshung, Monica; Arús, Bernardo A; Wong, Kelly C Y; Glasl, Sarah; Ntziachristos, Vasilis; Warmer, Martin; McLaughlin, Ryan R; Bruns, Oliver T; Sletten, Ellen M
IF
发表日期：2020
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Combining BRAF inhibition with oncolytic herpes simplex virus enhances the immune-mediated antitumor therapy of BRAF-mutant thyroid cancer

BRAF 抑制与溶瘤单纯疱疹病毒相结合可增强 BRAF 突变型甲状腺癌的免疫介导抗肿瘤治疗

期刊:Journal for ImmunoTherapy of Cancer
影响因子:10.3
doi:10.1136/jitc-2020-000698
Eva Crespo-Rodriguez, Katharina Bergerhoff, Galabina Bozhanova, Shane Foo, Emmanuel C Patin, Harriet Whittock, Richard Buus, Syed Haider, Gareth Muirhead, Khin Thway, Kate Newbold, Robert S Coffin, Richard G Vile, Dae Kim, Martin McLaughlin, Alan A Melcher, Kevin J Harrington, Malin Pedersen
信号转导
免疫
微生物学
疱疹
发表日期：2020
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The PERK Inhibitor GSK2606414 Enhances Reovirus Infection in Head and Neck Squamous Cell Carcinoma via an ATF4-Dependent Mechanism

PERK 抑制剂 GSK2606414 通过 ATF4 依赖性机制增强头颈部鳞状细胞癌中的呼肠孤病毒感染

期刊:Molecular Therapy-Oncolytics
影响因子:5.3
doi:10.1016/j.omto.2020.01.001
Martin McLaughlin, Malin Pedersen, Victoria Roulstone, Katharina F Bergerhoff, Henry G Smith, Harriet Whittock, Joan N Kyula, Magnus T Dillon, Hardev S Pandha, Richard Vile, Alan A Melcher, Kevin J Harrington
信号转导
微生物学
肿瘤
头颈癌
其它细胞
IHC
MAPK/ERK
发表日期：2020
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PD-1 Blockade Following Isolated Limb Perfusion with Vaccinia Virus Prevents Local and Distant Relapse of Soft-tissue Sarcoma

PD-1 阻断后进行牛痘病毒离体肢体灌注可预防软组织肉瘤局部和远处复发

期刊:Clinical Cancer Research
影响因子:10
doi:10.1158/1078-0432.CCR-18-3767
Henry G Smith, David Mansfield, Victoria Roulstone, Joan N Kyula-Currie, Martin McLaughlin, Radhika R Patel, Katharina F Bergerhoff, James T Paget, Magnus T Dillon, Aadil Khan, Alan Melcher, Khin Thway, Kevin J Harrington, Andrew J Hayes
微生物学
肿瘤
发表日期：2019
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