日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A genome-wide CRISPR screen identifies GRA38 as a key regulator of lipid homeostasis during Toxoplasma gondii adaptation to lipid-rich conditions

全基因组 CRISPR 筛选鉴定出 GRA38 是弓形虫适应富含脂质环境过程中脂质稳态的关键调控因子

Bitew, Mebratu A; Paredes-Santos, Tatiana C; Maru, Parag; Krishnamurthy, Shruthi; Wang, Yifan; Sangaré, Lamba O; Duley, Samuel; Yamaryo-Botté, Yoshiki; Botté, Cyrille Y; Saeij, Jeroen P J

Surface antigen SAG1 mediates Toxoplasma gondii fitness and host cell attachment in IFNγ-stimulated cells

表面抗原SAG1介导弓形虫在IFNγ刺激细胞中的适应性和宿主细胞黏附。

Cohen, Olivia; Maru, Parag; Liang, Qinli; Saeij, Jeroen P J

A genome-wide CRISPR screen identifies GRA38 as a key regulator of lipid homeostasis during Toxoplasma gondii adaptation to lipid-rich conditions.

全基因组 CRISPR 筛选发现 GRA38 是弓形虫适应富含脂质的环境过程中脂质稳态的关键调节因子

Bitew Mebratu A, Paredes-Santos Tatiana C, Maru Parag, Krishnamurthy Shruthi, Wang Yifan, Sangaré Lamba O, Duley Samuel, Yamaryo-Botté Yoshiki, Botte Cyrille, Saeij Jeroen P J

CRISPR Screens Identify Toxoplasma Genes That Determine Parasite Fitness in Interferon Gamma-Stimulated Human Cells.

CRISPR筛选鉴定出弓形虫基因,这些基因决定了寄生虫在γ干扰素刺激的人类细胞中的适应性

Krishnamurthy Shruthi, Maru Parag, Wang Yifan, Bitew Mebratu A, Mukhopadhyay Debanjan, Yamaryo-Botté Yoshiki, Paredes-Santos Tatiana C, Sangaré Lamba O, Swale Christopher, Botté Cyrille Y, Saeij Jeroen P J

TDR Targets 6: driving drug discovery for human pathogens through intensive chemogenomic data integration

TDR 目标 6:通过深度整合化学基因组学数据推动人类病原体药物研发

Urán Landaburu, Lionel; Berenstein, Ariel J; Videla, Santiago; Maru, Parag; Shanmugam, Dhanasekaran; Chernomoretz, Ariel; Agüero, Fernán