日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Direct Readout of Multivalent Chromatin Reader-Nucleosome Interactions by Nucleosome Mass Spectrometry

利用核小体质谱法直接读取多价染色质读取器-核小体相互作用

Lee, Alexander S; Fisher, Nickolas P; Marunde, Matthew R; Su, Pei; Khan, Laiba F; Ezell, Ryan J; Gillespie, Zachary B; Graham, Bria; Taylor, Hailey F; Onuoha, Ugochi C; Su, Taojunfeng; Jooß, Kevin; Schachner, Luis F; Fuchs, Harrison A; Noll, Kelsey; Meiners, Matthew J; Cheek, Marcus A; Burg, Jonathan M; Sun, Zu-Wen; Musselman, Catherine A; Keogh, Michael-Christopher; Kelleher, Neil L

Different modes of engagement with the nucleosome acidic patch yield distinct functional outcomes

与核小体酸性区域相互作用的不同方式会产生不同的功能结果。

Chakraborty, Ujani; Saccone, Emma Christina; Cruz-Becerra, Grisel; Khan, Laiba F; Arslanovic, Nina; Aguilar, Rhiannon; Gloor, Susan L; Hunt, Sabrina R; Folkwein, Heather J; Husby, Natalia Ledo; Maier, Keith E; Marunde, Matthew R; Schomburg, Noah K; Vaidya, Anup; Cowles, Martis W; Venters, Bryan J; Kassavetis, George; Sun, Zu-Wen; Kadonaga, James T; Armache, Jean-Paul; Keogh, Michael-Christopher; Tyler, Jessica K

Nucleosome context regulates chromatin reader preference

核小体环境调控染色质阅读器的偏好性

Matthew R Marunde ,Irina K Popova ,Nathan W Hall ,Anup Vaidya ,James R Bone ,Brandon A Boone ,Peter J Brown ,Ryan J Ezell ,Tessa M Firestone ,Harrison A Fuchs ,Elisa Gibson ,Zachary B Gillespie ,Susan L Gloor ,Allison R Hickman ,Sarah A Howard ,Natalia Ledo Husby ,Victoria T Hsiung ,Andrea L Johnstone ,Laiba F Khan ,Krzysztof Krajewski ,Alexander S Lee ,Eileen T McAnarney ,Keith E Maier ,Danielle N Maryanski ,Jamie L McCuiston ,Kelsey E Noll ,Katherine Novitzky ,Emily F Patteson ,Keli L Rodriguez ,Julio C Sanchez ,Luis F Schachner ,Catherine E Smith ,Lu Sun ,Hailey F Taylor ,Rachel Watson ,Hannah E Willis ,Catherine A Musselman ,Bryan J Venters ,Marcus A Cheek ,Matthew J Meiners ,Zu-Wen Sun ,Neil L Kelleher ,Martis W Cowles ,Ellen N Weinzapfel ,Michael-Christopher Keogh ,Jonathan M Burg

Multivalent binding of the tardigrade Dsup protein to chromatin promotes yeast survival and longevity upon exposure to oxidative damage

水熊虫Dsup蛋白与染色质的多价结合促进酵母在暴露于氧化损伤后存活和延长寿命。

Aguilar, Rhiannon R; Khan, Laiba F; Cummins, Christopher K; Arslanovic, Nina; Grauer, Thea; Birmingham, Kaylah; Kasliwal, Kritika; Posnikoff, Spike D L; Chakraborty, Ujani; Hickman, Allison R; Watson, Rachel; Ezell, Ryan J; Hunt, Sabrina R; Mukhsinova, Laylo; Willis, Hannah E; Cowles, Martis W; Garner, Richard; Shim, Abraham; Gutierrez, J Ignacio; Venters, Bryan J; Marunde, Matthew R; Strahl, Brian D; Keogh, Michael-Christopher; Tyler, Jessica K

Histone H3 N-terminal recognition by the PHD finger of PHRF1 is required for proper DNA damage response

PHRF1的PHD指结构域识别组蛋白H3 N端是DNA损伤反应所必需的。

Jain, Kanishk; Kougnassoukou Tchara, Pata-Eting; Khan, Abid; Mengistalem, Amanuel B; Holland, Aidan P; Bowman, Christopher N; Marunde, Matthew R; Engel, Tiffany A; Popova, Irina K; Cooke, Spencer W; Krajewski, Krzysztof; Keogh, Michael-Christopher; Lambert, Jean-Philippe; Strahl, Brian D

Signaling induced biophysical disruption of repressed chromatin domains drives immune cell fate

信号诱导的抑制性染色质区域的生物物理破坏驱动免疫细胞命运

de Paz, Alexia Martínez; Chin, Christopher R; Ketavarapu, Mythili; Sun, Yuchen; Marunde, Matthew R; Chang, Jeremy T; Khan, Laiba; Cohen, John; Yang, Rui; Bale, Michael J; Daman, Andrew W; Kumar, Vigneshwari E; Jiang, Chenyang; Ahimovic, Dughan J; Owyong, Mark; Ravishankar, Arjun; Wong, Wilfred; Shih, Rochelle; Graham, Bria; Smith, Catherine E; Karagianidis, Ioannis; Cerchietti, Leandro; Flowers, Christopher R; Green, Michael R; Mason, Christopher E; Sun, Joseph C; Martin-Trujillo, Alejandro; Niec, Rachel E; Long, Yicheng; Keogh, Michael-Christopher; Liu, Shixin; Béguelin, Wendy; Leslie, Christina S; Melnick, Ari M; Josefowicz, Steven Z

Heterochromatin fidelity is a therapeutic vulnerability in lymphoma and other human cancers

异染色质的完整性是淋巴瘤和其他人类癌症治疗中的一个软肋。

Najia, Mohamad Ali; Jha, Deepak K; Zhang, Cheng; Laurent, Benoit; Kubaczka, Caroline; Markel, Arianna; Li, Christopher; Morris, Vivian; Tompkins, Allison; Hensch, Luca; Qin, Yue; Chapuy, Bjoern; Huang, Yu-Chung; Morse, Michael; Marunde, Matthew R; Vaidya, Anup; Gillespie, Zachary B; Howard, Sarah A; North, Trista E; Dominguez, Daniel; Keogh, Michael-Christopher; Schlaeger, Thorsten M; Shi, Yang; Li, Hu; Shipp, Margaret M; Blainey, Paul C; Daley, George Q

Gestational diabetes augments group B Streptococcus infection by disrupting maternal immunity and the vaginal microbiota

妊娠期糖尿病会破坏母体免疫力和阴道微生物群,从而加剧B族链球菌感染。

Vicki Mercado-Evans ,Marlyd E Mejia ,Jacob J Zulk ,Samantha Ottinger ,Zainab A Hameed ,Camille Serchejian ,Madelynn G Marunde ,Clare M Robertson ,Mallory B Ballard ,Simone H Ruano ,Natalia Korotkova ,Anthony R Flores ,Kathleen A Pennington ,Kathryn A Patras

Nucleosome conformation dictates the histone code

核小体构象决定组蛋白密码

Matthew R Marunde #, Harrison A Fuchs #, Jonathan M Burg, Irina K Popova, Anup Vaidya, Nathan W Hall, Ellen N Weinzapfel, Matthew J Meiners, Rachel Watson, Zachary B Gillespie, Hailey F Taylor, Laylo Mukhsinova, Ugochi C Onuoha, Sarah A Howard, Katherine Novitzky, Eileen T McAnarney, Krzysztof Kraje

The CECR2 bromodomain displays distinct binding modes to select for acetylated histone proteins versus non-histone ligands.

CECR2 溴结构域表现出不同的结合模式,能够选择性地结合乙酰化组蛋白和非组蛋白配体

Phillips Margaret, Cook Elizabeth D, Marunde Matthew R, Tonelli Marco, Khan Laiba, Henrickson Amy, Lignos James M, Stein Janet L, Stein Gary S, Frietze Seth, Demeler Borries, Glass Karen C