日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Discovery of SARS-CoV-2 papain-like protease (PLpro) inhibitors with efficacy in a murine infection model

发现对小鼠感染模型有效的 SARS-CoV-2 木瓜蛋白酶样蛋白酶 (PLpro) 抑制剂

期刊:Science Advances
影响因子:11.7
doi:10.1126/sciadv.ado4288
Michelle R Garnsey, Matthew C Robinson, Luong T Nguyen, Rhonda Cardin, Joseph Tillotson, Ellene Mashalidis, Aijia Yu, Lisa Aschenbrenner, Amanda Balesano, Amin Behzadi, Britton Boras, Jeanne S Chang, Heather Eng, Andrew Ephron, Tim Foley, Kristen K Ford, James M Frick, Scott Gibson, Li Hao, Brett Hu
免疫
新冠
发表日期：2024
文献求助 收藏

Synthesis of macrocyclic nucleoside antibacterials and their interactions with MraY

大环核苷类抗菌剂的合成及其与MraY的相互作用

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-022-35227-z
Nakaya, Takeshi; Yabe, Miyuki; Mashalidis, Ellene H; Sato, Toyotaka; Yamamoto, Kazuki; Hikiji, Yuta; Katsuyama, Akira; Shinohara, Motoko; Minato, Yusuke; Takahashi, Satoshi; Horiuchi, Motohiro; Yokota, Shin-Ichi; Lee, Seok-Yong; Ichikawa, Satoshi
发表日期：2022
文献求助 收藏

Synthesis and evaluation of cyclopentane-based muraymycin analogs targeting MraY

合成和评价靶向MraY的环戊烷类muraymycin类似物

期刊:European Journal of Medicinal Chemistry
影响因子:5.9
doi:10.1016/j.ejmech.2021.113272
Kwak, Seung-Hwa; Lim, Won Young; Hao, Aili; Mashalidis, Ellene H; Kwon, Do-Yeon; Jeong, Pyeonghwa; Kim, Mi Jung; Lee, Seok-Yong; Hong, Jiyong
发表日期：2021
文献求助 收藏

Structures of Bacterial MraY and Human GPT Provide Insights into Rational Antibiotic Design

细菌MraY和人类GPT的结构为合理抗生素设计提供了见解

期刊:Journal of Molecular Biology
影响因子:4.5
doi:10.1016/j.jmb.2020.03.017
Mashalidis, Ellene H; Lee, Seok-Yong
微生物学
Human
发表日期：2020
文献求助 收藏

GlcNAc-1-P-transferase-tunicamycin complex structure reveals basis for inhibition of N-glycosylation

GlcNAc-1-P-转移酶-衣霉素复合物结构揭示了N-糖基化抑制的基础

期刊:Nature Structural & Molecular Biology
影响因子:10.1
doi:10.1038/s41594-018-0031-y
Yoo, Jiho; Mashalidis, Ellene H; Kuk, Alvin C Y; Yamamoto, Kazuki; Kaeser, Benjamin; Ichikawa, Satoshi; Lee, Seok-Yong
发表日期：2018
文献求助 收藏

Crystal structure of the MOP flippase MurJ in an inward-facing conformation.

MOP 翻转酶 MurJ 的晶体结构呈内向构象

期刊:Nature Structural & Molecular Biology
影响因子:10.1
doi:10.1038/nsmb.3346
Kuk Alvin C Y, Mashalidis Ellene H, Lee Seok-Yong
免疫/内分泌
发表日期：2017
文献求助 收藏

Molecular insights into the binding of coenzyme F420 to the conserved protein Rv1155 from Mycobacterium tuberculosis

结核分枝杆菌辅酶F420与保守蛋白Rv1155结合的分子机制研究

期刊:Protein Science
影响因子:5.2
doi:10.1002/pro.2645
Mashalidis, Ellene H; Gittis, Apostolos G; Tomczak, Aurelie; Abell, Chris; Barry, Clifton E 3rd; Garboczi, David N
发表日期：2015
文献求助 收藏

Biofragments: an approach towards predicting protein function using biologically related fragments and its application to Mycobacterium tuberculosis CYP126

生物片段：一种利用生物相关片段预测蛋白质功能的方法及其在结核分枝杆菌CYP126中的应用

期刊:Chembiochem
影响因子:2.8
doi:10.1002/cbic.201300697
Hudson, Sean A; Mashalidis, Ellene H; Bender, Andreas; McLean, Kirsty J; Munro, Andrew W; Abell, Chris
发表日期：2014
文献求助 收藏

Rv2607 from Mycobacterium tuberculosis is a pyridoxine 5'-phosphate oxidase with unusual substrate specificity

结核分枝杆菌的Rv2607是一种具有异常底物特异性的吡哆醇5'-磷酸氧化酶。

期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0027643
Mashalidis, Ellene H; Mukherjee, Tathagata; Sledź, Paweł; Matak-Vinković, Dijana; Boshoff, Helena; Abell, Chris; Barry, Clifton E 3rd
发表日期：2011
文献求助 收藏