Somatic variants activating the RAS-MAPK pathway confer susceptibility to hippocampal sclerosis in drug-resistant epilepsy
激活 RAS-MAPK 通路的体细胞变异会使耐药性癫痫患者易患海马硬化。
期刊:
影响因子:
doi:10.64898/2026.04.06.716727
Mashburn-Warren, Lauren; Holub, Ashton; Sran, Sahibjot; Ramadesikan, Swetha; Suh, Keaton R; Thompson, Allison; Anderson, James J; Rivaldi, Adithe; Zavarella, Ari R; Chandler, Megan; Daley, Allison; Strawser, Corinne H; Garfinkle, Elizabeth A R; Pindrik, Jonathan; Shaikhouni, Ammar; Leonard, Jeffrey; Boué, Daniel R; Thomas, Diana L; Pierson, Christopher R; Mardis, Elaine R; Miller, Katherine E; Ostendorf, Adam P; Koboldt, Daniel C; Bedrosian, Tracy A
信号转导
RAS
细胞生物学
神经科学
癫痫
MAPK/ERK