日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Pharmacologic and Oncohistone Inhibition of SETD2 Converge on Genomic Instability

SETD2的药理学抑制和肿瘤组蛋白抑制最终导致基因组不稳定性

Paparella, Alyssa T; Boice, Ashley G; Park, In Young; Nishad, Rajkishor; Tripathi, Durga; Nelson, Seth A; Pietryk, Edward W; Jang, H Josh; Frew, Ian J; Rathmell, W Kimryn; Mason, Frank M; Coarfa, Cristian; Dere, Ruhee; Walker, Cheryl Lyn

Lysine demethylase 4A is a centrosome-associated protein required for centrosome integrity and genomic stability.

赖氨酸去甲基酶 4A 是一种中心体相关蛋白,对中心体的完整性和基因组稳定性至关重要。

Chowdhury Pratim, Wang Xiaoli, Han Richard I, Motrapu Manga, Boice Ashley G, Nakatani Yuya, Vargas-Hernandez Sofia, Love Julia F, Chew Claude, Grimm Sandra L, Mezquita Dereck, Mason Frank M, Martinez Elisabeth D, Coarfa Cristian, Walker Cheryl L, Gustavsson Anna-Karin, Dere Ruhee

A SETD2-CDK1-lamin axis maintains nuclear morphology and genome stability.

SETD2-CDK1-核纤层蛋白轴维持细胞核形态和基因组稳定性。

Khan Abid, Zhang Cheng, Nguyen Phu G, Metts James M, Collins Lucas C, Jain Kanishk, Mills C Allie, Vlach Logan, Li Kelin, Brademeyer Amanda L, Bowman Brittany M, Major Michael B, Aubé Jeffrey, Herring Laura E, Rathmell W Kimryn, Mason Frank M, Davis Ian J, Zhang Qing, Strahl Brian D

Impaired oxidative phosphorylation drives primary tumor escape and metastasis

氧化磷酸化受损驱动原发肿瘤逃逸和转移

Arner, Emily N; Jennings, Erin Q; Crooks, Daniel R; Ricketts, Christopher J; Wolf, Melissa M; Cottam, Matthew A; Fisher-Gupta, Emilie L; Lang, Martin; Maio, Nunziata; Shibata, Yuki; Krystofiak, Evan S; Vlach, Logan M; Hatem, Zaid; Blatt, Alexander M; Heintzman, Darren R; Sewell, Allison E; Hathaway, Emma S; Steiner, KayLee K; Ye, Xiang; Schaefer, Samuel; Bacigalupa, Zachary A; Linehan, W Marston; Beckermann, Kathryn E; Mason, Frank M; Idrees, Kamran; Rathmell, W Kimryn; Rathmell, Jeffrey C

Subset-specific mitochondrial stress and DNA damage shape T cell responses to fever and inflammation.

亚群特异性线粒体应激和 DNA 损伤影响 T 细胞对发热和炎症的反应

Heintzman Darren R, Sinard Rachael C, Fisher Emilie L, Ye Xiang, Patterson Andrew R, Elasy Joel H, Voss Kelsey, Chi Channing, Sugiura Ayaka, Rodriguez-Garcia Gabriel J, Chowdhury Nowrin U, Arner Emily N, Krystoviak Evan S, Mason Frank M, Toudji Yasmine T, Steiner KayLee K, Khan Wasay, Olson Lana M, Jones Angela L, Hong Hanna S, Bass Lindsay, Beier Katherine L, Deng Wentao, Lyssiotis Costas A, Newcomb Dawn C, Bick Alexander G, Rathmell W Kimryn, Wilson John T, Rathmell Jeffrey C

Drug screening in human physiologic medium identifies uric acid as an inhibitor of rigosertib efficacy

在人体生理介质中进行的药物筛选发现,尿酸是rigosertib疗效的抑制剂。

Rawat, Vipin; DeLear, Patrick; Prashanth, Prarthana; Ozgurses, Mete Emir; Tebeje, Anteneh; Burns, Philippa A; Conger, Kelly O; Solís, Christopher; Hasnain, Yasir; Novikova, Anna; Endress, Jennifer E; González-Sánchez, Paloma; Dong, Wentao; Stephanopoulos, Greg; DeNicola, Gina M; Harris, Isaac S; Sept, David; Mason, Frank M; Coloff, Jonathan L

Lysine Demethylase 4A is a Centrosome Associated Protein Required for Centrosome Integrity and Genomic Stability

赖氨酸去甲基酶4A是一种中心体相关蛋白,对中心体完整性和基因组稳定性至关重要。

Chowdhury, Pratim; Wang, Xiaoli; Love, Julia F; Vargas-Hernandez, Sofia; Nakatani, Yuya; Grimm, Sandra L; Mezquita, Dereck; Mason, Frank M; Martinez, Elisabeth D; Coarfa, Cristian; Walker, Cheryl L; Gustavsson, Anna-Karin; Dere, Ruhee

Cell-programmed nutrient partitioning in the tumour microenvironment

肿瘤微环境中细胞程序化的营养分配

Bradley I Reinfeld # ,Matthew Z Madden # ,Melissa M Wolf ,Anna Chytil ,Jackie E Bader ,Andrew R Patterson ,Ayaka Sugiura ,Allison S Cohen ,Ahmed Ali ,Brian T Do ,Alexander Muir ,Caroline A Lewis ,Rachel A Hongo ,Kirsten L Young ,Rachel E Brown ,Vera M Todd ,Tessa Huffstater ,Abin Abraham ,Richard T O'Neil ,Matthew H Wilson ,Fuxue Xin ,M Noor Tantawy ,W David Merryman ,Rachelle W Johnson ,Christopher S Williams ,Emily F Mason ,Frank M Mason ,Katherine E Beckermann ,Matthew G Vander Heiden ,H Charles Manning ,Jeffrey C Rathmell ,W Kimryn Rathmell

Actomyosin Pulsing in Tissue Integrity Maintenance during Morphogenesis

肌动球蛋白脉冲在形态发生过程中维持组织完整性

Coravos, Jonathan S; Mason, Frank M; Martin, Adam C

RhoA GTPase inhibition organizes contraction during epithelial morphogenesis.

RhoA GTPase 抑制在表皮形态发生过程中组织收缩

Mason Frank M, Xie Shicong, Vasquez Claudia G, Tworoger Michael, Martin Adam C