日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The Decrease of Uch-L1 Activity Is a Common Mechanism Responsible for Aβ 42 Accumulation in Alzheimer's and Vascular Disease

Uch-L1 活性降低是导致阿尔茨海默病和血管疾病中 Aβ 42 积累的常见机制

Michela Guglielmotto, Debora Monteleone, Valeria Vasciaveo, Ivan Enrico Repetto, Giusi Manassero, Massimo Tabaton, Elena Tamagno

Dual Mechanism of Toxicity for Extracellular Injection of Tau Oligomers versus Monomers in Human Tau Mice

人类 Tau 小鼠细胞外注射 Tau 寡聚体与单体的双重毒性机制

Giusi Manassero, Michela Guglielmotto, Debora Monteleone, Valeria Vasciaveo, Olena Butenko, Elena Tamagno, Ottavio Arancio, Massimo Tabaton

Beta-amyloid 1-42 monomers, but not oligomers, produce PHF-like conformation of Tau protein

β-淀粉样蛋白 1-42 单体(而非低聚物)可产生 PHF 样构象的 Tau 蛋白

Giusi Manassero, Michela Guglielmotto, Raluca Zamfir, Roberta Borghi, Laura Colombo, Mario Salmona, George Perry, Patrizio Odetti, Ottavio Arancio, Elena Tamagno, Massimo Tabaton

Aβ1-42 monomers or oligomers have different effects on autophagy and apoptosis

Aβ1-42单体或寡聚体对自噬和细胞凋亡的影响不同

Michela Guglielmotto, Debora Monteleone, Antonio Piras, Valeria Valsecchi, Marta Tropiano, Stefania Ariano, Michele Fornaro, Alessandro Vercelli, Julien Puyal, Ottavio Arancio, Massimo Tabaton, Elena Tamagno

RNA polymerase III drives alternative splicing of the potassium channel-interacting protein contributing to brain complexity and neurodegeneration

RNA聚合酶III驱动钾通道相互作用蛋白的选择性剪接,导致大脑复杂性和神经退化

Sara Massone, Irene Vassallo, Manuele Castelnuovo, Gloria Fiorino, Elena Gatta, Mauro Robello, Roberta Borghi, Massimo Tabaton, Claudio Russo, Giorgio Dieci, Ranieri Cancedda, Aldo Pagano

A novel origin for granulovacuolar degeneration in aging and Alzheimer's disease: parallels to stress granules

衰老和阿尔茨海默病中颗粒空泡变性的新起源:与应激颗粒相似

Rudy J Castellani, Yashi Gupta, Baiyang Sheng, Sandra L Siedlak, Peggy Lr Harris, Jeff M Coller, George Perry, Hyoung-Gon Lee, Massimo Tabaton, Mark A Smith, Xinglong Wang, Xiongwei Zhu

Oxidative stress activates a positive feedback between the gamma- and beta-secretase cleavages of the beta-amyloid precursor protein

氧化应激激活 β-淀粉样蛋白前体蛋白的 γ-和 β-分泌酶裂解之间的正反馈

Elena Tamagno, Michela Guglielmotto, Manuela Aragno, Roberta Borghi, Riccardo Autelli, Luca Giliberto, Giuseppe Muraca, Oliviero Danni, Xiongwei Zhu, Mark A Smith, George Perry, Dong-Gyu Jo, Mark P Mattson, Massimo Tabaton