Mast Natalia相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

Retinal phenotype of APOB100 transgenic mice on a Western diet with human-like hyperlipidemia and cholesterol crystals in the retina and choroid

喂食西式饮食的APOB100转基因小鼠的视网膜表型表现为类似人类的高脂血症，视网膜和脉络膜中出现胆固醇结晶。

期刊:Lab Animal

影响因子:3.9

doi:10.1038/s41684-026-01693-x

El-Darzi, Nicole; Dorweiler, Tim F; Mast, Natalia; Busik, Julia; Pikuleva, Irina A

发表日期：2026

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Dietary effects on the retina of hamsters.

饮食对仓鼠视网膜的影响

期刊:FASEB Journal

影响因子:4.2

doi:10.1096/fj.202403390R

El-Darzi Nicole, Mast Natalia, Li Yong, Pikuleva Irina A

发表日期：2025

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Quantitative characterizations of the cholesterol-related pathways in the retina and brain of hamsters

仓鼠视网膜和大脑中胆固醇相关通路定量表征

期刊:Journal of Lipid Research

影响因子:4.1

doi:10.1016/j.jlr.2023.100401

Mast, Natalia; El-Darzi, Nicole; Li, Yong; Pikuleva, Irina A

发表日期：2023

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The Hydroxylation Position Rather than Chirality Determines How Efavirenz Metabolites Activate Cytochrome P450 46A1 In Vitro

羟基化位置而非手性决定了依非韦伦代谢物如何在体外激活细胞色素P450 46A1

期刊:Drug Metabolism and Disposition

doi:10.1124/dmd.122.000874

Mast, Natalia; Fotinich, Anna; Pikuleva, Irina A

细胞生物学

发表日期：2022

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CYP46A1-dependent and independent effects of efavirenz treatment

依非韦伦治疗的CYP46A1依赖性和非依赖性效应

期刊:Brain Communications

影响因子:4.5

doi:10.1093/braincomms/fcaa180

Mast, Natalia; El-Darzi, Nicole; Petrov, Alexey M; Li, Young; Pikuleva, Irina A

发表日期：2020

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Synthesis and pharmacokinetic study of a (11)C-labeled cholesterol 24-hydroxylase inhibitor using 'in-loop' [(11)C]CO(2) fixation method

利用“环内”[(11)C]CO(2)固定法合成(11)C标记的胆固醇24-羟化酶抑制剂并进行药代动力学研究

期刊:Bioorganic & Medicinal Chemistry Letters

影响因子:2.2

doi:10.1016/j.bmcl.2020.127068

Chen, Zhen; Chen, Jiahui; Mast, Natalia; Rong, Jian; Deng, Xiaoyun; Shao, Tuo; Fu, Hualong; Yu, Qingzhen; Sun, Jiyun; Shao, Yihan; Josephson, Lee; Collier, Thomas Lee; Pikuleva, Irina; Liang, Steven H

发表日期：2020

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The key genes, phosphoproteins, processes, and pathways affected by efavirenz-activated CYP46A1 in the amyloid-decreasing paradigm of efavirenz treatment

在依非韦伦治疗降低淀粉样蛋白的模式中，依非韦伦激活的CYP46A1影响的关键基因、磷酸化蛋白、过程和通路。

期刊:FASEB Journal

影响因子:4.2

doi:10.1096/fj.201900092R

Petrov, Alexey M; Mast, Natalia; Li, Yong; Pikuleva, Irina A

发表日期：2019

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N,N-Dimethyl-3β-hydroxycholenamide Reduces Retinal Cholesterol via Partial Inhibition of Retinal Cholesterol Biosynthesis Rather Than its Liver X Receptor Transcriptional Activity

N,N-二甲基-3β-羟基胆酰胺通过部分抑制视网膜胆固醇生物合成而非其肝X受体转录活性来降低视网膜胆固醇水平。

期刊:Frontiers in Pharmacology

影响因子:4.8

doi:10.3389/fphar.2018.00827

El-Darzi, Nicole; Astafev, Artem; Mast, Natalia; Saadane, Aicha; Lam, Morrie; Pikuleva, Irina A

发表日期：2018

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Retinal Cholesterol Content Is Reduced in Simvastatin-Treated Mice Due to Inhibited Local Biosynthesis Albeit Increased Uptake of Serum Cholesterol

辛伐他汀治疗的小鼠视网膜胆固醇含量降低，这是由于局部生物合成受到抑制，尽管血清胆固醇的摄取增加。

期刊:Drug Metabolism and Disposition

doi:10.1124/dmd.118.083345

Mast, Natalia; Bederman, Ilya R; Pikuleva, Irina A

发表日期：2018

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Drugs and Scaffold That Inhibit Cytochrome P450 27A1 In Vitro and In Vivo

体外和体内抑制细胞色素P450 27A1的药物和支架

期刊:Molecular Pharmacology

doi:10.1124/mol.117.110742

Lam, Morrie; Mast, Natalia; Pikuleva, Irina A

细胞生物学

发表日期：2018

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