日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Development of a robust, physiologically relevant neuronal tau aggregation assay for tau-related drug discovery

开发一种稳健且生理相关的神经元tau蛋白聚集检测方法,用于tau蛋白相关药物的发现

Jessica W Wu ,Katherine Titterton ,Rebecca Sebastian ,Nandini Romanul ,Kiran Yanamandra ,Bryan Mastis ,Rui Chang ,Saurabh Khasnavis ,Taekyung Kwon ,Yating Chai ,Justine D Manos ,Christina N Preiss ,Miwei Hu ,Alessandra M Welker ,Fan Liao ,Tammy Dellovade ,Eric Karran ,Xavier Langlois

Pharmacokinetic/Pharmacodynamic Modeling of a Cell-Penetrating Peptide Phosphorodiamidate Morpholino Oligomer in mdx Mice

细胞穿透肽磷酸二酰胺吗啉低聚物在 mdx 小鼠中的药代动力学/药效学建模

Marie Claire Mukashyaka, Chia-Ling Wu, Kristin Ha, Jianbo Zhang, Jenna Wood, Samantha Foley, Bryan Mastis, Nino Jungels, Huadong Sun, Mohammad Shadid, Shawn Harriman, John R Hadcock

Widespread AAV1- and AAV2-mediated transgene expression in the nonhuman primate brain: implications for Huntington's disease

非人灵长类动物大脑中广泛的AAV1和AAV2介导的转基因表达:对亨廷顿病的启示

Hadaczek, Piotr; Stanek, Lisa; Ciesielska, Agnieszka; Sudhakar, Vivek; Samaranch, Lluis; Pivirotto, Philip; Bringas, John; O'Riordan, Catherine; Mastis, Bryan; San Sebastian, Waldy; Forsayeth, John; Cheng, Seng H; Bankiewicz, Krystof S; Shihabuddin, Lamya S

Silencing mutant huntingtin by adeno-associated virus-mediated RNA interference ameliorates disease manifestations in the YAC128 mouse model of Huntington's disease

利用腺相关病毒介导的RNA干扰沉默突变亨廷顿蛋白可改善亨廷顿病YAC128小鼠模型的疾病症状。

Stanek, Lisa M; Sardi, Sergio P; Mastis, Bryan; Richards, Amy R; Treleaven, Christopher M; Taksir, Tatyana; Misra, Kuma; Cheng, Seng H; Shihabuddin, Lamya S