Allospecific splenic Tr1 cells drive effector T cell exhaustion through up-regulated Areg-EGFR signaling to promote transplant tolerance
同种异体脾脏Tr1细胞通过上调Areg-EGFR信号通路驱动效应T细胞耗竭，从而促进移植耐受。
期刊:Science Advances
影响因子:12.5
doi:10.1126/sciadv.aea0567
Singh, Amar; Herman, Adam; Dey, Devanjan; Menge, Samuel; Singh, Shilpi; Tran, Anna; Matson, Anders; Mourad, Ahmed; Rangarajan, Parthasarathy; Masuria, Ravi; Sato, Naoya; Vadnais, Sarah; Rao, Joseph Sushil; Singh, Gatikrushna; Graham, Melanie L; Ramachandran, Sabarinathan; Hering, Bernhard J
T细胞
信号转导
EGF
EGFR
T细胞
细胞生物学
免疫/内分泌
