日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A hidden cysteine in Fis1 targeted to prevent excessive mitochondrial fission and dysfunction under oxidative stress.

Fis1 中隐藏的半胱氨酸可防止氧化应激下线粒体过度分裂和功能障碍

Pokhrel Suman, Heo Gwangbeom, Mathews Irimpan, Yokoi Shun, Matsui Tsutomu, Mitsutake Ayori, Wakatsuki Soichi, Mochly-Rosen Daria

Covalent Drug Binding in Live Cells Monitored by Mid-Infrared Quantum Cascade Laser Spectroscopy: Photoactive Yellow Protein as a Model System

利用中红外量子级联激光光谱法监测活细胞中共价药物结合:以光敏黄蛋白为模型系统

Mukherjee, Srijit; Fried, Steven D E; Hong, Nathalie Y; Bagheri, Nahal; Kozuch, Jacek; Mathews, Irimpan I; Kirsh, Jacob M; Boxer, Steven G

Machine Learning-Guided Identification of PET Hydrolases from Natural Diversity

利用机器学习从自然多样性中鉴定PET水解酶

Norton-Baker, Brenna; Komp, Evan; Gado, Japheth E; Denton, Mackenzie C R; Mathews, Irimpan I; Murphy, Natasha P; Erickson, Erika; Storment, Olateju O; Sarangi, Ritimukta; Gauthier, Nicholas P; McGeehan, John E; Beckham, Gregg T

Designing Cyclic Nitrogen-Bridged Sulfonamides with Anti-Cancer Activity

设计具有抗癌活性的环状氮桥磺酰胺

Grau, Benedikt W; Dheeraj, Arpit; Mathews, Irimpan I; Tailor, Dhanir; Malhotra, Sanjay V

A Novel Unorthodox Dimeric Primary Enoyl-CoA Reductase Structure

新型非正统二聚体初级烯酰辅酶A还原酶结构

Kulakman, Cahine; Mathews, Irimpan I; Yoshikuni, Yasuo; Wakatsuki, Soichi; DeMirci, Hasan

Covalent Drug Binding in Live Cells Monitored by Mid-IR Quantum Cascade Laser Spectroscopy: Photoactive Yellow Protein as a Model System

利用中红外量子级联激光光谱法监测活细胞中的共价药物结合:以光敏黄蛋白为模型系统

Mukherjee, Srijit; Fried, Steven D E; Hong, Nathalie Y; Bagheri, Nahal; Kozuch, Jacek; Mathews, Irimpan I; Kirsh, Jacob M; Boxer, Steven G

Enhanced active-site electric field accelerates enzyme catalysis

增强的活性位点电场加速酶催化

Zheng, Chu; Ji, Zhe; Mathews, Irimpan I; Boxer, Steven G

Protein sequence design with a learned potential

利用学习潜力进行蛋白质序列设计

Anand, Namrata; Eguchi, Raphael; Mathews, Irimpan I; Perez, Carla P; Derry, Alexander; Altman, Russ B; Huang, Po-Ssu

Protein Electric Fields Enable Faster and Longer-Lasting Covalent Inhibition of β-Lactamases

蛋白质电场能够实现对β-内酰胺酶更快、更持久的共价抑制。

Ji, Zhe; Kozuch, Jacek; Mathews, Irimpan I; Diercks, Christian S; Shamsudin, Yasmin; Schulz, Mirjam A; Boxer, Steven G

Energetic Basis and Design of Enzyme Function Demonstrated Using GFP, an Excited-State Enzyme

利用激发态酶GFP阐明酶功能的能量基础和设计

Lin, Chi-Yun; Romei, Matthew G; Mathews, Irimpan I; Boxer, Steven G