Mathews Paul M相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

Increased Neuronal Expression of the Early Endosomal Adaptor APPL1 Replicates Alzheimer's Disease-Related Endosomal and Synaptic Dysfunction with Cholinergic Neurodegeneration.

早期内体衔接蛋白 APPL1 的神经元表达增加，可重现阿尔茨海默病相关的内体和突触功能障碍以及胆碱能神经退行性变

期刊:Journal of Neuroscience

doi:10.1523/JNEUROSCI.2331-24.2025

Jiang Ying, Sachdeva Kuldeep, Goulbourne Chris N, Berg Martin J, Peddy James, Stavrides Philip H, Pensalfini Anna, Pawlik Monika, Malampati Sandeep, Whyte Lauren, Basavarajappa Balapal S, Subbanna Shivakumar, Bleiwas Cynthia, Smiley John F, Mathews Paul M, Nixon Ralph A

发表日期：2025

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Aging, Rather than Genotype, Is the Principal Contributor to Differential Gene Expression Within Targeted Replacement APOE2, APOE3, and APOE4 Mouse Brain

衰老而非基因型才是导致靶向替换APOE2、APOE3和APOE4小鼠脑内基因表达差异的主要因素。

期刊:Brain Sciences

影响因子:2.8

doi:10.3390/brainsci15101117

Labuza, Amanda; Pidikiti, Harshitha; Alldred, Melissa J; Ibrahim, Kyrillos W; Peng, Katherine Y; Pasato, Jonathan; Heguy, Adriana; Mathews, Paul M; Ginsberg, Stephen D

发表日期：2025

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Increased neuronal expression of the early endosomal adaptor APPL1 replicates Alzheimer's Disease-related endosomal and synaptic dysfunction with cholinergic neurodegeneration

早期内体衔接蛋白APPL1在神经元中的表达增加，会重现阿尔茨海默病相关的内体和突触功能障碍以及胆碱能神经退行性变。

doi:10.1101/2024.09.19.613736

Jiang, Ying; Sachdeva, Kuldeep; Goulbourne, Chris N; Berg, Martin J; Peddy, James; Stavrides, Philip H; Pensalfini, Anna; Pawlik, Monika; Malampati, Sandeep; Whyte, Lauren; Basavarajappa, Balapal S; Shivakumar, Subbanna; Bleiwas, Cynthia; Smiley, John F; Mathews, Paul M; Nixon, Ralph A

阿尔茨海默症

发表日期：2025

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Apolipoprotein E2 Expression Alters Endosomal Pathways in a Mouse Model With Increased Brain Exosome Levels During Aging.

在衰老过程中，载脂蛋白 E2 的表达会改变小鼠模型中脑外泌体水平升高时的内体通路

影响因子:2.5

doi:10.1111/tra.12937

Peng Katherine Y, Liemisa Braison, Pasato Jonathan, D'Acunzo Pasquale, Pawlik Monika, Heguy Adriana, Penikalapati Sai C, Labuza Amanda, Pidikiti Harshitha, Alldred Melissa J, Ginsberg Stephen D, Levy Efrat, Mathews Paul M

免疫/内分泌

发表日期：2024

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Human Apolipoprotein E Genotype Differentially Affects Olfactory Behavior and Sensory Physiology in Mice

人类载脂蛋白E基因型对小鼠嗅觉行为和感觉生理的影响存在差异

期刊:Neuroscience

影响因子:2.8

doi:10.1016/j.neuroscience.2018.04.009

East, Brett S; Fleming, Gloria; Peng, Kathy; Olofsson, Jonas K; Levy, Efrat; Mathews, Paul M; Wilson, Donald A

发表日期：2018

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Cystatin C in aging and in Alzheimer's disease

胱抑素C与衰老和阿尔茨海默病

期刊:Ageing Research Reviews

影响因子:12.4

doi:10.1016/j.arr.2016.06.003

Mathews, Paul M; Levy, Efrat

阿尔茨海默症

发表日期：2016

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Brain-Wide Insulin Resistance, Tau Phosphorylation Changes, and Hippocampal Neprilysin and Amyloid-β Alterations in a Monkey Model of Type 1 Diabetes

1型糖尿病猴模型中全脑胰岛素抵抗、tau蛋白磷酸化改变以及海马脑啡肽酶和β-淀粉样蛋白改变

期刊:Journal of Neuroscience

doi:10.1523/JNEUROSCI.4640-14.2016

Morales-Corraliza, Jose; Wong, Harrison; Mazzella, Matthew J; Che, Shaoli; Lee, Sang Han; Petkova, Eva; Wagner, Janice D; Hemby, Scott E; Ginsberg, Stephen D; Mathews, Paul M

免疫/内分泌

发表日期：2016

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Partial BACE1 reduction in a Down syndrome mouse model blocks Alzheimer-related endosomal anomalies and cholinergic neurodegeneration: role of APP-CTF

在唐氏综合征小鼠模型中，部分降低BACE1表达可阻断阿尔茨海默病相关的内体异常和胆碱能神经退行性变：APP-CTF的作用

期刊:Neurobiology of Aging

影响因子:3.5

doi:10.1016/j.neurobiolaging.2015.11.013

Jiang, Ying; Rigoglioso, Andrew; Peterhoff, Corrinne M; Pawlik, Monika; Sato, Yutaka; Bleiwas, Cynthia; Stavrides, Philip; Smiley, John F; Ginsberg, Stephen D; Mathews, Paul M; Levy, Efrat; Nixon, Ralph A

阿尔茨海默症

发表日期：2016

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Endogenous murine Aβ increases amyloid deposition in APP23 but not in APPPS1 transgenic mice

内源性小鼠Aβ可增加APP23转基因小鼠而非APPPS1转基因小鼠的淀粉样蛋白沉积。

期刊:Neurobiology of Aging

影响因子:3.5

doi:10.1016/j.neurobiolaging.2015.03.011

Mahler, Jasmin; Morales-Corraliza, Jose; Stolz, Julia; Skodras, Angelos; Radde, Rebecca; Duma, Carmen C; Eisele, Yvonne S; Mazzella, Matthew J; Wong, Harrison; Klunk, William E; Nilsson, K Peter R; Staufenbiel, Matthias; Mathews, Paul M; Jucker, Mathias; Wegenast-Braun, Bettina M

发表日期：2015

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Reduction of β-amyloid and γ-secretase by calorie restriction in female Tg2576 mice

热量限制可降低雌性Tg2576小鼠体内β-淀粉样蛋白和γ-分泌酶的含量

期刊:Neurobiology of Aging

doi:10.1016/j.neurobiolaging.2014.10.043

Schafer, Marissa J; Alldred, Melissa J; Lee, Sang Han; Calhoun, Michael E; Petkova, Eva; Mathews, Paul M; Ginsberg, Stephen D

发表日期：2015

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