Wnt inhibitory factor 1 is epigenetically silenced in human osteosarcoma, and targeted disruption accelerates osteosarcomagenesis in mice
Wnt 抑制因子 1 在人类骨肉瘤中表观遗传沉默,而靶向破坏会加速小鼠骨肉瘤的发生
期刊:Journal of Clinical Investigation
影响因子:13.3
doi:10.1172/JCI37175
Maya Kansara, Michael Tsang, Laurent Kodjabachian, Natalie A Sims, Melanie K Trivett, Mathias Ehrich, Alexander Dobrovic, John Slavin, Peter F M Choong, Paul J Simmons, Igor B Dawid, David M Thomas
信号转导
肿瘤
骨肉瘤
Wnt/β-Catenin
Human