日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A µ-opioid receptor modulator that works cooperatively with naloxone.

一种与纳洛酮协同作用的μ-阿片受体调节剂

O'Brien Evan S, Rangari Vipin Ashok, El Daibani Amal, Eans Shainnel O, Hammond Haylee R, White Elizabeth, Wang Haoqing, Shiimura Yuki, Krishna Kumar Kaavya, Jiang Qianru, Appourchaux Kevin, Huang Weijiao, Zhang Chensong, Kennedy Brandon J, Mathiesen Jesper M, Che Tao, McLaughlin Jay P, Majumdar Susruta, Kobilka Brian K

Allosteric modulation and G-protein selectivity of the Ca(2+)-sensing receptor.

Ca(2+)敏感受体的变构调节和G蛋白选择性

He Feng, Wu Cheng-Guo, Gao Yang, Rahman Sabrina N, Zaoralová Magda, Papasergi-Scott Makaía M, Gu Ting-Jia, Robertson Michael J, Seven Alpay B, Li Lingjun, Mathiesen Jesper M, Skiniotis Georgios

Mechanistic insights into G-protein coupling with an agonist-bound G-protein-coupled receptor.

对激动剂结合的 G 蛋白偶联受体的 G 蛋白偶联机制的深入了解

Batebi Hossein, Pérez-Hernández Guillermo, Rahman Sabrina N, Lan Baoliang, Kamprad Antje, Shi Mingyu, Speck David, Tiemann Johanna K S, Guixà-González Ramon, Reinhardt Franziska, Stadler Peter F, Papasergi-Scott Makaía M, Skiniotis Georgios, Scheerer Patrick, Kobilka Brian K, Mathiesen Jesper M, Liu Xiangyu, Hildebrand Peter W

Structural Insights into the Process of GPCR-G Protein Complex Formation.

GPCR-G蛋白复合物形成过程的结构解析

Liu Xiangyu, Xu Xinyu, Hilger Daniel, Aschauer Philipp, Tiemann Johanna K S, Du Yang, Liu Hongtao, Hirata Kunio, Sun Xiaoou, Guixà-González Ramon, Mathiesen Jesper M, Hildebrand Peter W, Kobilka Brian K

Crystal structure of the µ-opioid receptor bound to a morphinan antagonist.

μ-阿片受体与吗啡烷拮抗剂结合的晶体结构

Manglik Aashish, Kruse Andrew C, Kobilka Tong Sun, Thian Foon Sun, Mathiesen Jesper M, Sunahara Roger K, Pardo Leonardo, Weis William I, Kobilka Brian K, Granier Sébastien

Crystal structure of the β2 adrenergic receptor-Gs protein complex.

β2肾上腺素能受体-Gs蛋白复合物的晶体结构

Rasmussen Søren G F, DeVree Brian T, Zou Yaozhong, Kruse Andrew C, Chung Ka Young, Kobilka Tong Sun, Thian Foon Sun, Chae Pil Seok, Pardon Els, Calinski Diane, Mathiesen Jesper M, Shah Syed T A, Lyons Joseph A, Caffrey Martin, Gellman Samuel H, Steyaert Jan, Skiniotis Georgios, Weis William I, Sunahara Roger K, Kobilka Brian K