日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Primidone: a clinically promising candidate for the treatment of psoriasis

扑米酮:一种在临床上很有前景的银屑病治疗候选药物

Theresa Riebeling ,Benedikt Kolbrink ,Rebecca Philippsen ,Eileen Dahlke ,Tom Delanghe ,Franziska Theilig ,Agatha Schwarz ,Roland Schmitt ,Mathieu J M Bertrand ,Ulrich Kunzendorf ,Stefan Krautwald

RIPK1 is dispensable for cell death regulation in β-cells during hyperglycemia

高血糖期间,RIPK1 对 β 细胞的细胞死亡调节是可有可无的

Önay Veli, Öykü Kaya, Ana Beatriz Varanda, Ximena Hildebrandt, Peng Xiao, Yann Estornes, Matea Poggenberg, Yuan Wang, Manolis Pasparakis, Mathieu J M Bertrand, Henning Walczak, Alessandro Annibaldi, Alessandra K Cardozo, Nieves Peltzer

NINJ1 is activated by cell swelling to regulate plasma membrane permeabilization during regulated necrosis

NINJ1 在细胞肿胀时被激活,在调节坏死过程中调节质膜通透性

Yves Dondelinger, Dario Priem, Jon Huyghe, Tom Delanghe, Peter Vandenabeele, Mathieu J M Bertrand

From PERK to RIPK1: Design, synthesis and evaluation of novel potent and selective necroptosis inhibitors

从 PERK 到 RIPK1:新型强效选择性坏死凋亡抑制剂的设计、合成和评估

Camilla Scarpellini, Sophie Valembois, Kenneth Goossens, Mike Vadi, Caroline Lanthier, Greta Klejborowska, Pieter Van Der Veken, Hans De Winter, Mathieu J M Bertrand, Koen Augustyns

ATG9A prevents TNF cytotoxicity by an unconventional lysosomal targeting pathway

ATG9A 通过非常规溶酶体靶向途径预防 TNF 细胞毒性

Jon Huyghe #, Dario Priem #, Lisette Van Hove, Barbara Gilbert, Jürgen Fritsch, Yasuo Uchiyama, Esther Hoste, Geert van Loo, Mathieu J M Bertrand

Endocytic membrane repair by ESCRT-III controls antigen export to the cytosol during antigen cross-presentation

ESCRT-III 进行的内吞膜修复控制抗原交叉呈递过程中抗原向胞质溶胶的输出

Marine Gros, Elodie Segura, Derek C Rookhuizen, Blandine Baudon, Sandrine Heurtebise-Chrétien, Nina Burgdorf, Mathieu Maurin, Eugene A Kapp, Richard J Simpson, Patrycja Kozik, Jose A Villadangos, Mathieu J M Bertrand, Marianne Burbage, Sebastian Amigorena

The Impact of RIPK1 Kinase Inhibition on Atherogenesis: A Genetic and a Pharmacological Approach

RIPK1 激酶抑制对动脉粥样硬化形成的影响:遗传学和药理学方法

Pauline Puylaert, Isabelle Coornaert, Cédric H G Neutel, Yves Dondelinger, Tom Delanghe, Mathieu J M Bertrand, Pieter-Jan Guns, Guido R Y De Meyer, Wim Martinet

Antioxidant and food additive BHA prevents TNF cytotoxicity by acting as a direct RIPK1 inhibitor

抗氧化剂和食品添加剂 BHA 可作为直接 RIPK1 抑制剂,防止 TNF 细胞毒性

Tom Delanghe, Jon Huyghe, Seungheon Lee, Dario Priem, Samya Van Coillie, Barbara Gilbert, Sze Men Choi, Peter Vandenabeele, Alexei Degterev, Gregory D Cuny, Yves Dondelinger, Mathieu J M Bertrand

Autophosphorylation at serine 166 regulates RIP kinase 1-mediated cell death and inflammation

丝氨酸 166 位点的自身磷酸化调节 RIP 激酶 1 介导的细胞死亡和炎症

Lucie Laurien, Masahiro Nagata, Hannah Schünke, Tom Delanghe, Janica L Wiederstein, Snehlata Kumari, Robin Schwarzer, Teresa Corona, Marcus Krüger, Mathieu J M Bertrand, Vangelis Kondylis, Manolis Pasparakis

OTULIN Prevents Liver Inflammation and Hepatocellular Carcinoma by Inhibiting FADD- and RIPK1 Kinase-Mediated Hepatocyte Apoptosis

OTULIN 通过抑制 FADD 和 RIPK1 激酶介导的肝细胞凋亡来预防肝脏炎症和肝细胞癌

Lien Verboom, Arne Martens, Dario Priem, Esther Hoste, Mozes Sze, Hanna Vikkula, Lisette Van Hove, Sofie Voet, Jana Roels, Jonathan Maelfait, Laura Bongiovanni, Alain de Bruin, Charlotte L Scott, Yvan Saeys, Manolis Pasparakis, Mathieu J M Bertrand, Geert van Loo