日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Phage-assisted evolution of allosteric protein switches

噬菌体辅助的变构蛋白开关进化

Southern, Nicholas T; von Bachmann, Anna; Hovsepyan, Alisa; Griebl, Marielouise; Wolf, Benedict; Lemmen, Nina; Kroell, Ann-Sophie; Westermann, Simon; Mathony, Jan; Niopek, Dominik

Modular engineering of thermoresponsive allosteric proteins

热响应变构蛋白的模块化工程

Kroell, Ann-Sophie; Hoffmann, Kira H; Motzkus, Nikolas A; Lemmen, Nina; Happ, Nele; Wolf, Benedict; von Bachmann, Anna-Lisa; Southern, Nicholas; Vogd, Felicitas; Aschenbrenner, Sabine; Niopek, Dominik; Mathony, Jan

Bioswitches: Towards programmable, on-demand control of therapeutic proteins

生物开关:迈向对治疗性蛋白质进行可编程、按需控制

Wolf, Benedict; Mathony, Jan; Niopek, Dominik

A foundation model to predict and capture human cognition

用于预测和捕捉人类认知能力的基础模型

Binz, Marcel; Akata, Elif; Bethge, Matthias; Brändle, Franziska; Callaway, Fred; Coda-Forno, Julian; Dayan, Peter; Demircan, Can; Eckstein, Maria K; Éltető, Noémi; Griffiths, Thomas L; Haridi, Susanne; Jagadish, Akshay K; Ji-An, Li; Kipnis, Alexander; Kumar, Sreejan; Ludwig, Tobias; Mathony, Marvin; Mattar, Marcelo; Modirshanechi, Alireza; Nath, Surabhi S; Peterson, Joshua C; Rmus, Milena; Russek, Evan M; Saanum, Tankred; Schubert, Johannes A; Schulze Buschoff, Luca M; Singhi, Nishad; Sui, Xin; Thalmann, Mirko; Theis, Fabian J; Truong, Vuong; Udandarao, Vishaal; Voudouris, Konstantinos; Wilson, Robert; Witte, Kristin; Wu, Shuchen; Wulff, Dirk U; Xiong, Huadong; Schulz, Eric

Rational engineering of allosteric protein switches by in silico prediction of domain insertion sites.

通过计算机预测结构域插入位点,对变构蛋白开关进行合理设计

Wolf Benedict, Shehu Pegi, Brenker Luca, von Bachmann Anna-Lisa, Kroell Ann-Sophie, Southern Nicholas, Holderbach Stefan, Eigenmann Joshua, Aschenbrenner Sabine, Mathony Jan, Niopek Dominik

A modular toolbox for the optogenetic deactivation of transcription

用于光遗传学转录失活的模块化工具箱

Muench, Philipp; Fiumara, Matteo; Southern, Nicholas; Coda, Davide; Aschenbrenner, Sabine; Correia, Bruno; Gräff, Johannes; Niopek, Dominik; Mathony, Jan

Engineering the Link: From Genome Interaction Maps to Functional Insight

构建连接:从基因组相互作用图谱到功能洞察

Petersen, Frido; Westermann, Simon; Smialkovska, Valeriia; Mathony, Jan; Feldmann, Angelika; Niopek, Dominik

A deep mutational scanning platform to characterize the fitness landscape of anti-CRISPR proteins

一个用于表征抗CRISPR蛋白适应性图谱的深度突变扫描平台

Stadelmann, Tobias; Heid, Daniel; Jendrusch, Michael; Mathony, Jan; Aschenbrenner, Sabine; Rosset, Stéphane; Correia, Bruno E; Niopek, Dominik

Transformative Experiences, Cognitive Modelling and Affective Forecasting

变革性体验、认知建模和情感预测

Mathony, Marvin; Messerli, Michael

Optogenetic control of Neisseria meningitidis Cas9 genome editing using an engineered, light-switchable anti-CRISPR protein

使用工程化的光可切换抗 CRISPR 蛋白进行脑膜炎奈瑟菌 Cas9 基因组编辑的光遗传学控制

Mareike D Hoffmann, Jan Mathony, Julius Upmeier Zu Belzen, Zander Harteveld, Sabine Aschenbrenner, Christina Stengl, Dirk Grimm, Bruno E Correia, Roland Eils, Dominik Niopek