日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Anti-HIV-1 activity of a tripodal receptor that recognizes mannose oligomers

识别甘露糖寡聚体的三脚架受体的抗HIV-1活性

Rivero-Buceta, Eva; Carrero, Paula; Casanova, Elena; Doyagüez, Elisa G; Madrona, Andrés; Quesada, Ernesto; Peréz-Pérez, María Jesús; Mateos, Raquel; Bravo, Laura; Mathys, Leen; Noppen, Sam; Kiselev, Evgeny; Marchand, Christophe; Pommier, Yves; Liekens, Sandra; Balzarini, Jan; Camarasa, María José; San-Félix, Ana

Several N-Glycans on the HIV Envelope Glycoprotein gp120 Preferentially Locate Near Disulphide Bridges and Are Required for Efficient Infectivity and Virus Transmission.

HIV包膜糖蛋白gp120上的几个N-糖链优先位于二硫键附近,是有效感染和病毒传播所必需的

Mathys Leen, Balzarini Jan

Deletion of the highly conserved N-glycan at Asn260 of HIV-1 gp120 affects folding and lysosomal degradation of gp120, and results in loss of viral infectivity.

HIV-1 gp120 的 Asn260 处高度保守的 N-聚糖的缺失会影响 gp120 的折叠和溶酶体降解,从而导致病毒感染力的丧失

Mathys Leen, François Katrien O, Quandte Matthias, Braakman Ineke, Balzarini Jan