日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The quantitative impact of 3'UTRs on gene expression

3'UTR对基因表达的定量影响

West, Jessica D; Smith, Hannah J; Vu, Luyen Tien; Fogarty, Elizabeth A; Matreyek, Kenneth A; Fowler, Douglas M; Grimson, Andrew

BOGO: A Proteome-Wide Gene Overexpression Platform for Discovering Rational Cancer Combination Therapies.

BOGO:用于发现合理癌症联合疗法的蛋白质组范围基因过表达平台

Jo Kyeong Beom, Alruwaili Mohammed M, Kim Da-Eun, Koh Yongjun, Kim Hyeyeon, You Kwontae, Kim Ji-Sun, Sane Saba, Guo Yanqi, Wright Jacob P, Lim Hyobin Julianne, Naranjo Maricris N, Coté Atina G, Roth Frederick P, Hill David E, Choi Jung-Hyun, Lee Hunsang, Matreyek Kenneth A, Farh Kyle K-H, Park Jong-Eun, Kim Hyunkyung, Bakin Andrei V, Kim Dae-Kyum

Evidence of antigenic drift in the fusion machinery core of SARS-CoV-2 spike

SARS-CoV-2刺突蛋白融合机制核心中存在抗原漂移的证据

Tan, Timothy J C; Verma, Abhishek K; Odle, Abby; Lei, Ruipeng; Meyerholz, David K; Matreyek, Kenneth A; Perlman, Stanley; Wong, Lok-Yin Roy; Wu, Nicholas C

Rapid Characterization of the Functional and Pharmacological Consequences of Cantú Syndrome K(ATP) Channel Mutations in Intact Cells

快速表征坎图综合征K(ATP)通道突变在完整细胞中的功能和药理学后果

Gao, Jian; McClenaghan, Conor; Matreyek, Kenneth A; Grange, Dorothy K; Nichols, Colin G

Shifting mutational constraints in the SARS-CoV-2 receptor-binding domain during viral evolution

SARS-CoV-2 受体结合域在病毒进化过程中突变约束的转变

Starr, Tyler N; Greaney, Allison J; Hannon, William W; Loes, Andrea N; Hauser, Kevin; Dillen, Josh R; Ferri, Elena; Farrell, Ariana Ghez; Dadonaite, Bernadeta; McCallum, Matthew; Matreyek, Kenneth A; Corti, Davide; Veesler, David; Snell, Gyorgy; Bloom, Jesse D

High-throughput identification of prefusion-stabilizing mutations in SARS-CoV-2 spike

利用高通量技术鉴定SARS-CoV-2刺突蛋白中融合前稳定突变

Tan, Timothy J C; Mou, Zongjun; Lei, Ruipeng; Ouyang, Wenhao O; Yuan, Meng; Song, Ge; Andrabi, Raiees; Wilson, Ian A; Kieffer, Collin; Dai, Xinghong; Matreyek, Kenneth A; Wu, Nicholas C

MHC class II transactivator CIITA induces cell resistance to Ebola virus and SARS-like coronaviruses

MHC II类转录激活因子CIITA诱导细胞对埃博拉病毒和SARS样冠状病毒的抵抗力

Bruchez, Anna; Sha, Ky; Johnson, Joshua; Chen, Li; Stefani, Caroline; McConnell, Hannah; Gaucherand, Lea; Prins, Rachel; Matreyek, Kenneth A; Hume, Adam J; Mühlberger, Elke; Schmidt, Emmett V; Olinger, Gene G; Stuart, Lynda M; Lacy-Hulbert, Adam

Massively parallel variant characterization identifies NUDT15 alleles associated with thiopurine toxicity

大规模并行变异特征分析鉴定出与硫嘌呤毒性相关的NUDT15等位基因

Suiter, Chase C; Moriyama, Takaya; Matreyek, Kenneth A; Yang, Wentao; Scaletti, Emma Rose; Nishii, Rina; Yang, Wenjian; Hoshitsuki, Keito; Singh, Minu; Trehan, Amita; Parish, Chris; Smith, Colton; Li, Lie; Bhojwani, Deepa; Yuen, Liz Y P; Li, Chi-Kong; Li, Chak-Ho; Yang, Yung-Li; Walker, Gareth J; Goodhand, James R; Kennedy, Nicholas A; Klussmann, Federico Antillon; Bhatia, Smita; Relling, Mary V; Kato, Motohiro; Hori, Hiroki; Bhatia, Prateek; Ahmad, Tariq; Yeoh, Allen E J; Stenmark, Pål; Fowler, Douglas M; Yang, Jun J

High-throughput discovery of trafficking-deficient variants in the cardiac potassium channel K(V)11.1

利用高通量技术发现心脏钾通道K(V)11.1中转运缺陷的变异体

Kozek, Krystian A; Glazer, Andrew M; Ng, Chai-Ann; Blackwell, Daniel; Egly, Christian L; Vanags, Loren R; Blair, Marcia; Mitchell, Devyn; Matreyek, Kenneth A; Fowler, Douglas M; Knollmann, Bjorn C; Vandenberg, Jamie I; Roden, Dan M; Kroncke, Brett M

Deep Mutational Scan of an SCN5A Voltage Sensor

SCN5A电压传感器的深度突变扫描

Glazer, Andrew M; Kroncke, Brett M; Matreyek, Kenneth A; Yang, Tao; Wada, Yuko; Shields, Tiffany; Salem, Joe-Elie; Fowler, Douglas M; Roden, Dan M