日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Integral approach to organelle profiling in human iPSC-derived cardiomyocytes enhances in vitro cardiac safety classification of known cardiotoxic compounds

对人诱导多能干细胞来源的心肌细胞进行细胞器分析的综合方法可增强已知心脏毒性化合物的体外心脏安全性分类。

Szabo, Brigitta R; Stein, Jeroen; Savchenko, Anna; Hutschalik, Thomas; Van Nieuwerburgh, Filip; Meese, Tim; Kosmidis, Georgios; Volders, Paul G A; Matsa, Elena

GJA5 and ATP1A1 perturbations recapitulate inflammation-related beat irregularities in iPSC-based atrial myocardium tissue model

GJA5 和 ATP1A1 的扰动可在基于 iPSC 的心房心肌组织模型中重现炎症相关的心律失常

Hutschalik, Thomas; Dasí, Albert; Riebel, Leto L; Wiendels, Maury; Bakker, Frederikus; Beckers, Lucas J A M; Kriege, Koen C; Valster, Susanne M; Vulders, Roland C M; Özgül, Ozan; Peyronnet, Rémi; Rodriguez, Blanca; Argenziano, Mariana; Schotten, Ulrich; Matsa, Elena

Using Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes as a Model to Study Trypanosoma cruzi Infection

利用人诱导多能干细胞衍生的心肌细胞作为模型研究克氏锥虫感染

Bozzi, Adriana; Sayed, Nazish; Matsa, Elena; Sass, Gabriele; Neofytou, Evgenios; Clemons, Karl V; Correa-Oliveira, Rodrigo; Stevens, David A; Wu, Joseph C

Passive Stretch Induces Structural and Functional Maturation of Engineered Heart Muscle as Predicted by Computational Modeling

被动拉伸诱导工程化心肌的结构和功能成熟,这与计算模型的预测相符

Abilez, Oscar J; Tzatzalos, Evangeline; Yang, Huaxiao; Zhao, Ming-Tao; Jung, Gwanghyun; Zöllner, Alexander M; Tiburcy, Malte; Riegler, Johannes; Matsa, Elena; Shukla, Praveen; Zhuge, Yan; Chour, Tony; Chen, Vincent C; Burridge, Paul W; Karakikes, Ioannis; Kuhl, Ellen; Bernstein, Daniel; Couture, Larry A; Gold, Joseph D; Zimmermann, Wolfram H; Wu, Joseph C

High-throughput screening of tyrosine kinase inhibitor cardiotoxicity with human induced pluripotent stem cells.

利用人诱导多能干细胞对酪氨酸激酶抑制剂心脏毒性进行高通量筛选

Sharma Arun, Burridge Paul W, McKeithan Wesley L, Serrano Ricardo, Shukla Praveen, Sayed Nazish, Churko Jared M, Kitani Tomoya, Wu Haodi, Holmström Alexandra, Matsa Elena, Zhang Yuan, Kumar Anusha, Fan Alice C, Del Álamo Juan C, Wu Sean M, Moslehi Javid J, Mercola Mark, Wu Joseph C

Induced pluripotent stem cells: at the heart of cardiovascular precision medicine

诱导多能干细胞:心血管精准医疗的核心

Chen, Ian Y; Matsa, Elena; Wu, Joseph C

Alternative approaches to generating cardiomyocytes are under development

目前正在开发生成心肌细胞的替代方法。

Chen, Ian Y; Matsa, Elena; Wu, Joseph C

Human Induced Pluripotent Stem Cells as a Platform for Personalized and Precision Cardiovascular Medicine

人类诱导多能干细胞作为个性化和精准心血管医学的平台

Matsa, Elena; Ahrens, John H; Wu, Joseph C

Modeling Cardiovascular Diseases with Patient-Specific Human Pluripotent Stem Cell-Derived Cardiomyocytes

利用患者特异性人类多能干细胞衍生的心肌细胞构建心血管疾病模型

Burridge, Paul W; Diecke, Sebastian; Matsa, Elena; Sharma, Arun; Wu, Haodi; Wu, Joseph C

Epigenetic Regulation of Phosphodiesterases 2A and 3A Underlies Compromised β-Adrenergic Signaling in an iPSC Model of Dilated Cardiomyopathy.

磷酸二酯酶 2A 和 3A 的表观遗传调控是扩张型心肌病 iPSC 模型中 β-肾上腺素能信号传导受损的基础

Wu Haodi, Lee Jaecheol, Vincent Ludovic G, Wang Qingtong, Gu Mingxia, Lan Feng, Churko Jared M, Sallam Karim I, Matsa Elena, Sharma Arun, Gold Joseph D, Engler Adam J, Xiang Yang K, Bers Donald M, Wu Joseph C