日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Recapitulating the adenoma-carcinoma sequence by selection of four spontaneous oncogenic mutations in mismatch-repair-deficient human colon organoids

通过在错配修复缺陷的人类结肠类器官中选择四种自发致癌突变来重现腺瘤-癌序列

Tomohiro Mizutani #, Matteo Boretto #, Sangho Lim, Jarno Drost, Diego Montiel González, Rurika Oka, Maarten H Geurts, Harry Begthel, Jeroen Korving, Johan H van Es, Ruben van Boxtel, Hans Clevers

Epidermal growth factor receptor (EGFR) is a target of the tumor-suppressor E3 ligase FBXW7

表皮生长因子受体 (EGFR) 是肿瘤抑制因子 E3 连接酶 FBXW7 的靶标

Matteo Boretto #, Maarten H Geurts #, Shashank Gandhi #, Ziliang Ma, Nadzeya Staliarova, Martina Celotti, Sangho Lim, Gui-Wei He, Rosemary Millen, Else Driehuis, Harry Begthel, Lidwien Smabers, Jeanine Roodhart, Johan van Es, Wei Wu, Hans Clevers

Evaluating CRISPR-based prime editing for cancer modeling and CFTR repair in organoids

评估基于 CRISPR 的 Prime Editing 在类器官中对癌症建模和 CFTR 修复的作用

Maarten H Geurts, Eyleen de Poel, Cayetano Pleguezuelos-Manzano, Rurika Oka, Léo Carrillo, Amanda Andersson-Rolf, Matteo Boretto, Jesse E Brunsveld, Ruben van Boxtel, Jeffrey M Beekman, Hans Clevers

Murine Endometrial Organoids to Model Chlamydia Infection

小鼠子宫内膜类器官模拟衣原体感染

R Clayton Bishop, Matteo Boretto, Melanie R Rutkowski, Hugo Vankelecom, Isabelle Derré

Coordination of germ layer lineage choice by TET1 during primed pluripotency

TET1在启动多能性过程中协调胚层谱系选择

Xinlong Luo ,Bernard K van der Veer ,Lei Sun ,Michela Bartoccetti ,Matteo Boretto ,Hugo Vankelecom ,Rita Khoueiry ,Kian Peng Koh

Functional expression of the mechanosensitive PIEZO1 channel in primary endometrial epithelial cells and endometrial organoids

机械敏感性 PIEZO1 通道在原发性子宫内膜上皮细胞和子宫内膜类器官中的功能性表达

Aurélie Hennes, Katharina Held, Matteo Boretto, Katrien De Clercq, Charlotte Van den Eynde, Arne Vanhie, Nele Van Ranst, Melissa Benoit, Catherine Luyten, Karen Peeraer, Carla Tomassetti, Christel Meuleman, Thomas Voets, Hugo Vankelecom, Joris Vriens

Major depletion of SOX2+ stem cells in the adult pituitary is not restored which does not affect hormonal cell homeostasis and remodelling

成人垂体中 SOX2+ 干细胞的大量耗竭无法恢复,这不会影响激素细胞稳态和重塑

Heleen Roose, Benoit Cox, Matteo Boretto, Conny Gysemans, Annelies Vennekens, Hugo Vankelecom