日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

EpiPro, a Novel, Synthetic, Activity-Regulated Promoter That Targets Hyperactive Neurons in Epilepsy for Gene Therapy Applications

EpiPro 是一种新型合成活性调节启动子,可靶向治疗癫痫中的过度活跃神经元,用于基因治疗应用

Cassidy T Burke, Iuliia Vitko, Justyna Straub, Elsa O Nylund, Agnieszka Gawda, Kathryn Blair, Kyle A Sullivan, Lara Ergun, Matteo Ottolini, Manoj K Patel, Edward Perez-Reyes

Endothelial pannexin 1-TRPV4 channel signaling lowers pulmonary arterial pressure in mice

内皮细胞 pannexin 1-TRPV4 通道信号降低小鼠肺动脉压

Zdravka Daneva, Matteo Ottolini, Yen Lin Chen, Eliska Klimentova, Maniselvan Kuppusamy, Soham A Shah, Richard D Minshall, Cheikh I Seye, Victor E Laubach, Brant E Isakson, Swapnil K Sonkusare

Mechanisms underlying selective coupling of endothelial Ca2+ signals with eNOS vs. IK/SK channels in systemic and pulmonary arteries

内皮 Ca2+ 信号与系统和肺动脉中的 eNOS 与 IK/SK 通道选择性耦合的潜在机制

Matteo Ottolini, Zdravka Daneva, Yen-Lin Chen, Eric L Cope, Ramesh B Kasetti, Gulab S Zode, Swapnil K Sonkusare

Inhibition of T-Type calcium channels in mEC layer II stellate neurons reduces neuronal hyperexcitability associated with epilepsy

抑制 mEC II 层星状神经元中的 T 型钙通道可降低与癫痫相关的神经元兴奋性

Aradhya Nigam, Nicholas J Hargus, Bryan S Barker, Matteo Ottolini, James A Hounshell, Edward H Bertram 3rd, Edward Perez-Reyes, Manoj K Patel

CACHD1 is an α2δ-Like Protein That Modulates CaV3 Voltage-Gated Calcium Channel Activity

CACHD1 是一种 α2δ 样蛋白,可调节 CaV3 电压门控钙通道活性

Graeme S Cottrell, Camille H Soubrane, James A Hounshell, Hong Lin, Venetia Owenson, Michael Rigby, Peter J Cox, Bryan S Barker, Matteo Ottolini, Selvi Ince, Claudia C Bauer, Edward Perez-Reyes, Manoj K Patel, Edward B Stevens, Gary J Stephens

Activation of murine pre-proglucagon-producing neurons reduces food intake and body weight

激活小鼠前胰高血糖素原产生神经元可减少食物摄入量和体重

Ronald P Gaykema, Brandon A Newmyer, Matteo Ottolini, Vidisha Raje, Daniel M Warthen, Philip S Lambeth, Maria Niccum, Ting Yao, Yiru Huang, Ira G Schulman, Thurl E Harris, Manoj K Patel, Kevin W Williams, Michael M Scott

Pro-excitatory alterations in sodium channel activity facilitate subiculum neuron hyperexcitability in temporal lobe epilepsy

钠通道活动的促兴奋性改变促进颞叶癫痫下托神经元的兴奋性

Bryan S Barker, Aradhya Nigam, Matteo Ottolini, Ronald P Gaykema, Nicholas J Hargus, Manoj K Patel

Aberrant Sodium Channel Currents and Hyperexcitability of Medial Entorhinal Cortex Neurons in a Mouse Model of SCN8A Encephalopathy

SCN8A 脑病小鼠模型中异常钠通道电流和内侧内嗅皮质神经元的兴奋性

Matteo Ottolini, Bryan S Barker, Ronald P Gaykema, Miriam H Meisler, Manoj K Patel

Genetically targeted magnetic control of the nervous system

基因靶向磁控神经系统

Michael A Wheeler, Cody J Smith, Matteo Ottolini, Bryan S Barker, Aarti M Purohit, Ryan M Grippo, Ronald P Gaykema, Anthony J Spano, Mark P Beenhakker, Sarah Kucenas, Manoj K Patel, Christopher D Deppmann, Ali D Güler

Activation of Pyramidal Neurons in Mouse Medial Prefrontal Cortex Enhances Food-Seeking Behavior While Reducing Impulsivity in the Absence of an Effect on Food Intake

小鼠内侧前额皮质中锥体神经元的激活可增强觅食行为,同时在不影响食物摄入量的情况下减少冲动性

Daniel M Warthen, Philip S Lambeth, Matteo Ottolini, Yingtang Shi, Bryan Scot Barker, Ronald P Gaykema, Brandon A Newmyer, Jonathan Joy-Gaba, Yu Ohmura, Edward Perez-Reyes, Ali D Güler, Manoj K Patel, Michael M Scott