日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Predictors of persisting symptoms after concussion in children following a traumatic brain injury: a longitudinal retrospective cohort study

儿童创伤性脑损伤后脑震荡持续症状的预测因素:一项纵向回顾性队列研究

Wilson, Rebecca; Jackson, Joni; Birnie, Kate; Ijaz, Sharea; Booker, Matthew; Burrell, Alex; Haythornthwaite, Giles; Hong, Jialan; Lyttle, Mark D; Pocock, Lucy; Scott, Lauren J; Williams, Cathy; Wright, Ingram; Savovic, Jelena; Mytton, Julie; Redaniel, Maria Theresa

Targeted protein degradation using chimeric human E2 ubiquitin-conjugating enzymes

使用嵌合人类 E2 泛素结合酶进行靶向蛋白质降解

Jonathan D Taylor, Nathalie Barrett, Sergio Martinez Cuesta, Katelyn Cassidy, Fiona Pachl, James Dodgson, Radhika Patel, Tuula M Eriksson, Aidan Riley, Matthew Burrell, Christin Bauer, D Gareth Rees, Raffaello Cimbro, Andrew X Zhang, Ralph R Minter, James Hunt, Sandrine Legg

Antibody-oligonucleotide conjugate achieves CNS delivery in animal models for spinal muscular atrophy

抗体-寡核苷酸偶联物在脊髓性肌萎缩动物模型中实现了中枢神经系统递送

Suzan M Hammond, Frank Abendroth, Larissa Goli, Jessica Stoodley, Matthew Burrell, George Thom, Ian Gurrell, Nina Ahlskog, Michael J Gait, Matthew Ja Wood, Carl I Webster

Brain pharmacokinetics of anti-transferrin receptor antibody affinity variants in rats determined using microdialysis

利用微透析法测定大鼠脑内抗转铁蛋白受体抗体亲和力变体的药代动力学

Hsueh-Yuan Chang ,Shengjia Wu ,Yingyi Li ,Wanying Zhang ,Matthew Burrell ,Carl I Webster ,Dhaval K Shah

A peptide derived from melanotransferrin delivers a protein-based interleukin 1 receptor antagonist across the BBB and ameliorates neuropathic pain in a preclinical model

一种源自黑素转铁蛋白的肽可跨 BBB 递送基于蛋白质的白细胞介素 1 受体拮抗剂,并在临床前模型中缓解神经性疼痛

George Thom, Mei-Mei Tian, Jon P Hatcher, Natalia Rodrigo, Matthew Burrell, Ian Gurrell, Timothy Z Vitalis, Thomas Abraham, Wilfred A Jefferies, Carl I Webster, Reinhard Gabathuler

Central inhibition of granulocyte-macrophage colony-stimulating factor is analgesic in experimental neuropathic pain

中枢抑制粒细胞巨噬细胞集落刺激因子对实验性神经性疼痛有镇痛作用

Louise S C Nicol, Peter Thornton, Jon P Hatcher, Colin P Glover, Carl I Webster, Matthew Burrell, Kessia Hammett, Clare A Jones, Matthew A Sleeman, Andrew Billinton, Iain Chessell

Intracellular sorting and transcytosis of the rat transferrin receptor antibody OX26 across the blood-brain barrier in vitro is dependent on its binding affinity

大鼠转铁蛋白受体抗体 OX26 体外跨血脑屏障的细胞内分选和转胞吞作用取决于其结合亲和力

Arsalan S Haqqani, George Thom, Matthew Burrell, Christie E Delaney, Eric Brunette, Ewa Baumann, Caroline Sodja, Anna Jezierski, Carl Webster, Danica B Stanimirovic

Enhanced delivery of IL-1 receptor antagonist to the central nervous system as a novel anti-transferrin receptor-IL-1RA fusion reverses neuropathic mechanical hypersensitivity

作为新型抗转铁蛋白受体-IL-1RA 融合物,增强 IL-1 受体拮抗剂向中枢神经系统的输送,可逆转神经性机械超敏反应

Carl I Webster, Jon Hatcher, Matthew Burrell, George Thom, Peter Thornton, Ian Gurrell, Iain Chessell

Sustained peripheral depletion of amyloid-β with a novel form of neprilysin does not affect central levels of amyloid-β

使用新型脑啡肽酶持续消耗外周β-淀粉样蛋白不会影响中枢β-淀粉样蛋白的水平

Simon J Henderson, Christin Andersson, Rajesh Narwal, Juliette Janson, Tom J Goldschmidt, Paulina Appelkvist, Anna Bogstedt, Ann-Charlott Steffen, Ulrich Haupts, Jan Tebbe, Per Ola Freskgård, Lutz Jermutus, Matthew Burrell, Susan B Fowler, Carl I Webster

Engineering neprilysin activity and specificity to create a novel therapeutic for Alzheimer's disease

设计脑啡肽酶活性和特异性以创造一种治疗阿尔茨海默病的新方法

Carl I Webster, Matthew Burrell, Lise-Lotte Olsson, Susan B Fowler, Sarah Digby, Alan Sandercock, Arjan Snijder, Jan Tebbe, Ulrich Haupts, Joanna Grudzinska, Lutz Jermutus, Christin Andersson