日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Antibody blockade of activin type II receptors preserves skeletal muscle mass and enhances fat loss during GLP-1 receptor agonism

激活素 II 型受体的抗体阻断可在 GLP-1 受体激动期间保持骨骼肌质量并增强脂肪流失

Elizabeth Nunn, Natasha Jaiswal, Matthew Gavin, Kahealani Uehara, Megan Stefkovich, Karima Drareni, Ryan Calhoun, Michelle Lee, Corey D Holman, Joseph A Baur, Patrick Seale, Paul M Titchenell

AKT controls protein synthesis and oxidative metabolism via combined mTORC1 and FOXO1 signalling to govern muscle physiology

AKT 通过 mTORC1 和 FOXO1 信号传导控制蛋白质合成和氧化代谢,从而调控肌肉生理学

Natasha Jaiswal, Matthew Gavin, Emanuele Loro, Jaimarie Sostre-Colón, Paul A Roberson, Kahealani Uehara, Nicole Rivera-Fuentes, Michael Neinast, Zoltan Arany, Scot R Kimball, Tejvir S Khurana, Paul M Titchenell

Activation of Liver mTORC1 Protects Against NASH via Dual Regulation of VLDL-TAG Secretion and De Novo Lipogenesis

肝脏 mTORC1 的激活可通过双重调节 VLDL-TAG 分泌和从头脂肪生成来预防 NASH

Kahealani Uehara, Jaimarie Sostre-Colón, Matthew Gavin, Dominic Santoleri, Kelly-Ann Leonard, René L Jacobs, Paul M Titchenell

Loss of FOXO transcription factors in the liver mitigates stress-induced hyperglycemia

肝脏中 FOXO 转录因子的缺失可减轻应激引起的高血糖

Anna E Garcia Whitlock, Jamarie Sostre-Colón, Matthew Gavin, Niels D Martin, Joseph A Baur, Carrie A Sims, Paul M Titchenell