日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

N-acetyl cysteine protects anti-melanoma cytotoxic T cells from exhaustion induced by rapid expansion via the downmodulation of Foxo1 in an Akt-dependent manner

N-乙酰半胱氨酸通过以 Akt 依赖的方式下调 Foxo1 来保护抗黑色素瘤细胞毒性 T 细胞免于因快速扩增而导致的衰竭

Matthew J Scheffel, Gina Scurti, Megan M Wyatt, Elizabeth Garrett-Mayer, Chrystal M Paulos, Michael I Nishimura, Christina Voelkel-Johnson

Lack of p53 Augments Antitumor Functions in Cytolytic T Cells

p53 缺乏可增强细胞溶解性 T 细胞的抗肿瘤功能

Anirban Banerjee #, Krishnamurthy Thyagarajan #, Shilpak Chatterjee #, Paramita Chakraborty, Pravin Kesarwani, Myroslawa Soloshchenko, Mazen Al-Hommrani, Kristina Andrijauskaite, Kelly Moxley, Harinarayanan Janakiraman, Matthew J Scheffel, Kristi Helke, Kent Armenson, Viswanathan Palanisamy, Mark P

Efficacy of Adoptive T-cell Therapy Is Improved by Treatment with the Antioxidant N-Acetyl Cysteine, Which Limits Activation-Induced T-cell Death

抗氧化剂 N-乙酰半胱氨酸可限制活化诱导的 T 细胞死亡,从而提高过继性 T 细胞疗法的疗效

Matthew J Scheffel, Gina Scurti, Patricia Simms, Elizabeth Garrett-Mayer, Shikhar Mehrotra, Michael I Nishimura, Christina Voelkel-Johnson

Expression of Ceramide Synthase 6 Transcriptionally Activates Acid Ceramidase in a c-Jun N-terminal Kinase (JNK)-dependent Manner

神经酰胺合酶 6 的表达以 c-Jun N 端激酶 (JNK) 依赖的方式转录激活酸性神经酰胺酶

Tejas S Tirodkar, Ping Lu, Aiping Bai, Matthew J Scheffel, Salih Gencer, Elizabeth Garrett-Mayer, Alicja Bielawska, Besim Ogretmen, Christina Voelkel-Johnson

T cells expanded in presence of IL-15 exhibit increased antioxidant capacity and innate effector molecules

在 IL-15 存在下扩增的 T 细胞表现出增强的抗氧化能力和先天效应分子

Navtej Kaur, Osama S Naga, Håkan Norell, Amir A Al-Khami, Matthew J Scheffel, Nitya G Chakraborty, Christina Voelkel-Johnson, Bijay Mukherji, Shikhar Mehrotra