A biomarker-stratified comparison of top-down versus accelerated step-up treatment strategies for patients with newly diagnosed Crohn's disease (PROFILE): a multicentre, open-label randomised controlled trial
一项针对新诊断克罗恩病患者的自上而下与加速阶梯式治疗策略的生物标志物分层比较研究（PROFILE）：一项多中心、开放标签的随机对照试验
期刊:Lancet Gastroenterology & Hepatology
影响因子:38.6
doi:10.1016/S2468-1253(24)00034-7
Noor, Nurulamin M; Lee, James C; Bond, Simon; Dowling, Francis; Brezina, Biljana; Patel, Kamal V; Ahmad, Tariq; Banim, Paul J; Berrill, James W; Cooney, Rachel; De La Revilla Negro, Juan; de Silva, Shanika; Din, Shahida; Durai, Dharmaraj; Gordon, John N; Irving, Peter M; Johnson, Matthew; Kent, Alexandra J; Kok, Klaartje B; Moran, Gordon W; Mowat, Craig; Patel, Pritash; Probert, Chris S; Raine, Tim; Saich, Rebecca; Seward, Abigail; Sharpstone, Dan; Smith, Melissa A; Subramanian, Sreedhar; Upponi, Sara S; Wiles, Alan; Williams, Horace R T; van den Brink, Gijs R; Vermeire, Séverine; Jairath, Vipul; D'Haens, Geert R; McKinney, Eoin F; Lyons, Paul A; Lindsay, James O; Kennedy, Nicholas A; Smith, Kenneth G C; Parkes, Miles
