日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Epitope-engineered human hematopoietic stem cells are shielded from CD123-targeted immunotherapy

表位工程化的造血干细胞可免受CD123靶向免疫疗法的影响

Romina Marone # ,Emmanuelle Landmann # ,Anna Devaux # ,Rosalba Lepore # ,Denis Seyres ,Jessica Zuin ,Thomas Burgold ,Corinne Engdahl ,Giuseppina Capoferri ,Alessandro Dell'Aglio ,Clément Larrue ,Federico Simonetta ,Julia Rositzka ,Manuel Rhiel ,Geoffroy Andrieux ,Danielle N Gallagher ,Markus S Schröder ,Amélie Wiederkehr ,Alessandro Sinopoli ,Valentin Do Sacramento ,Anna Haydn ,Laura Garcia-Prat ,Christopher Divsalar ,Anna Camus ,Liwen Xu ,Lorenza Bordoli ,Torsten Schwede ,Matthew Porteus ,Jérôme Tamburini ,Jacob E Corn ,Toni Cathomen ,Tatjana I Cornu ,Stefanie Urlinger ,Lukas T Jeker

iPSC-derived hypoimmunogenic tissue resident memory T cells mediate robust anti-tumor activity against cervical cancer

iPSC衍生的低免疫原性组织驻留记忆T细胞对宫颈癌具有强大的抗肿瘤活性

Yoshiki Furukawa,Midori Ishii,Jun Ando,Kazuya Ikeda,Kyomi J Igarashi,Shintaro Kinoshita,Yoko Azusawa,Tokuko Toyota,Tadahiro Honda,Mahito Nakanishi,Koichi Ohshima,Ayako Masuda,Emiko Yoshida,Mari Kitade,Matthew Porteus,Yasuhisa Terao,Hiromitsu Nakauchi,Miki Ando

Cas9-AAV6-engineered human mesenchymal stromal cells improved cutaneous wound healing in diabetic mice

Cas9-AAV6 工程化人类间充质基质细胞改善糖尿病小鼠的皮肤伤口愈合

Waracharee Srifa, Nina Kosaric, Alvaro Amorin, Othmane Jadi, Yujin Park, Sruthi Mantri, Joab Camarena, Geoffrey C Gurtner, Matthew Porteus

Role of human forkhead box P3 in early thymic maturation and peripheral T-cell homeostasis

人类叉头框 P3 在早期胸腺成熟和外周 T 细胞稳态中的作用

Francesca R Santoni de Sio, Laura Passerini, Silvia Restelli, Maria Maddalena Valente, Aleksandar Pramov, Maria Elena Maccari, Francesca Sanvito, Maria Grazia Roncarolo, Matthew Porteus, Rosa Bacchetta

MLL leukemia induction by t(9;11) chromosomal translocation in human hematopoietic stem cells using genome editing

利用基因组编辑技术在人类造血干细胞中诱导t(9;11)染色体易位,从而诱发MLL白血病。

Corina Schneidawind ,Johan Jeong ,Dominik Schneidawind ,In-Suk Kim ,Jesús Duque-Afonso ,Stephen Hon Kit Wong ,Masayuki Iwasaki ,Erin H Breese ,James L Zehnder ,Matthew Porteus ,Michael L Cleary

Phosphorylation of residues inside the SNARE complex suppresses secretory vesicle fusion

SNARE 复合物内残基的磷酸化抑制分泌囊泡融合

Seth Malmersjö, Serena Di Palma, Jiajie Diao, Ying Lai, Richard A Pfuetzner, Austin L Wang, Moira A McMahon, Arnold Hayer, Matthew Porteus, Bernd Bodenmiller, Axel T Brunger, Tobias Meyer

MLL leukemia induction by genome editing of human CD34+ hematopoietic cells

通过基因组编辑人类 CD34+ 造血细胞诱导 MLL 白血病

Corina Buechele, Erin H Breese, Dominik Schneidawind, Chiou-Hong Lin, Johan Jeong, Jesus Duque-Afonso, Stephen H K Wong, Kevin S Smith, Robert S Negrin, Matthew Porteus, Michael L Cleary

Stem Cell-Specific Mechanisms Ensure Genomic Fidelity within HSCs and upon Aging of HSCs

干细胞特异性机制确保 HSC 内和 HSC 老化时的基因组保真度

Bettina M Moehrle, Kalpana Nattamai, Andreas Brown, Maria C Florian, Marnie Ryan, Mona Vogel, Corinna Bliederhaeuser, Karin Soller, Daniel R Prows, Amir Abdollahi, David Schleimer, Dagmar Walter, Michael D Milsom, Peter Stambrook, Matthew Porteus, Hartmut Geiger

Phosphorylation of EXO1 by CDKs 1 and 2 regulates DNA end resection and repair pathway choice

CDKs 1 和 2 对 EXO1 的磷酸化调节 DNA 末端切除和修复途径选择

Nozomi Tomimatsu, Bipasha Mukherjee, Molly Catherine Hardebeck, Mariya Ilcheva, Cristel Vanessa Camacho, Janelle Louise Harris, Matthew Porteus, Bertrand Llorente, Kum Kum Khanna, Sandeep Burma