日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The mTORC1/4E-BP1 axis represents a critical signaling node during fibrogenesis

mTORC1/4E-BP1 轴代表纤维形成过程中的关键信号传导节点

Hannah V Woodcock, Jessica D Eley, Delphine Guillotin, Manuela Platé, Carmel B Nanthakumar, Matteo Martufi, Simon Peace, Gerard Joberty, Daniel Poeckel, Robert B Good, Adam R Taylor, Nico Zinn, Matthew Redding, Ellen J Forty, Robert E Hynds, Charles Swanton, Morten Karsdal, Toby M Maher, Andrew Fish

mTORC1 amplifies the ATF4-dependent de novo serine-glycine pathway to supply glycine during TGF-β1-induced collagen biosynthesis

mTORC1 扩增 ATF4 依赖的从头丝氨酸-甘氨酸途径,在 TGF-β1 诱导的胶原生物合成过程中提供甘氨酸

Brintha Selvarajah, Ilan Azuelos, Manuela Platé, Delphine Guillotin, Ellen J Forty, Greg Contento, Hannah V Woodcock, Matthew Redding, Adam Taylor, Gino Brunori, Pascal F Durrenberger, Riccardo Ronzoni, Andy D Blanchard, Paul F Mercer, Dimitrios Anastasiou, Rachel C Chambers