日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Sexual dimorphism in bidirectional SR-mitochondria crosstalk in ventricular cardiomyocytes

心室心肌细胞 SR 线粒体双向串扰的性别二态性

Richard T Clements #, Radmila Terentyeva #, Shanna Hamilton, Paul M L Janssen, Karim Roder, Benjamin Y Martin, Fruzsina Perger, Timothy Schneider, Zuzana Nichtova, Anindhya S Das, Roland Veress, Beth S Lee, Do-Gyoon Kim, Gideon Koren, Matthew S Stratton, Gyorgy Csordas, Federica Accornero, Andriy E

DUSP5-mediated inhibition of smooth muscle cell proliferation suppresses pulmonary hypertension and right ventricular hypertrophy

DUSP5介导的平滑肌细胞增殖抑制可抑制肺动脉高压和右心室肥大

Bradley S Ferguson, Sara A Wennersten, Kimberly M Demos-Davies, Marcello Rubino, Emma L Robinson, Maria A Cavasin, Matthew S Stratton, Andrew M Kidger, Tianjing Hu, Stephen M Keyse, Robert A McKnight, Robert H Lane, Eva S Nozik, Mary C M Weiser-Evans, Timothy A McKinsey

HDAC11 suppresses the thermogenic program of adipose tissue via BRD2

HDAC11 通过 BRD2 抑制脂肪组织的产热程序

Rushita A Bagchi, Bradley S Ferguson, Matthew S Stratton, Tianjing Hu, Maria A Cavasin, Lei Sun, Ying-Hsi Lin, Dianxin Liu, Pilar Londono, Kunhua Song, Maria F Pino, Lauren M Sparks, Steven R Smith, Philipp E Scherer, Sheila Collins, Edward Seto, Timothy A McKinsey

Class I HDACs control a JIP1-dependent pathway for kinesin-microtubule binding in cardiomyocytes

类 HDAC 控制心肌细胞中 JIP1 依赖的驱动蛋白-微管结合通路

Weston W Blakeslee, Ying-Hsi Lin, Matthew S Stratton, Philip D Tatman, Tianjing Hu, Bradley S Ferguson, Timothy A McKinsey

Overlapping and Divergent Actions of Structurally Distinct Histone Deacetylase Inhibitors in Cardiac Fibroblasts

结构不同的组蛋白去乙酰化酶抑制剂在心脏成纤维细胞中的重叠和发散作用

Katherine B Schuetze, Matthew S Stratton, Weston W Blakeslee, Michael F Wempe, Florence F Wagner, Edward B Holson, Yin-Ming Kuo, Andrew J Andrews, Tonya M Gilbert, Jacob M Hooker, Timothy A McKinsey

Signal-Dependent Recruitment of BRD4 to Cardiomyocyte Super-Enhancers Is Suppressed by a MicroRNA

MicroRNA 抑制 BRD4 对心肌细胞超增强子的信号依赖性募集

Matthew S Stratton, Charles Y Lin, Priti Anand, Philip D Tatman, Bradley S Ferguson, Sean T Wickers, Amrut V Ambardekar, Carmen C Sucharov, James E Bradner, Saptarsi M Haldar, Timothy A McKinsey

Discovery of novel small molecule inhibitors of cardiac hypertrophy using high throughput, high content imaging

利用高通量、高内涵成像发现新型心脏肥大小分子抑制剂

Brian G Reid, Matthew S Stratton, Samantha Bowers, Maria A Cavasin, Kimberley M Demos-Davies, Isidro Susano, Timothy A McKinsey

Promiscuous actions of small molecule inhibitors of the protein kinase D-class IIa HDAC axis in striated muscle

蛋白激酶 D-IIa 类 HDAC 轴的小分子抑制剂在横纹肌中的混合作用

Douglas D Lemon, Brooke C Harrison, Todd R Horn, Matthew S Stratton, Bradley S Ferguson, Michael F Wempe, Timothy A McKinsey

Reversal of severe angioproliferative pulmonary arterial hypertension and right ventricular hypertrophy by combined phosphodiesterase-5 and endothelin receptor inhibition

联合抑制磷酸二酯酶-5 和内皮素受体可逆转严重血管增生性肺动脉高压和右心室肥大

Maria A Cavasin, Kimberly M Demos-Davies, Katherine B Schuetze, Weston W Blakeslee, Matthew S Stratton, Rubin M Tuder, Timothy A McKinsey

Embryonic GABA(B) receptor blockade alters cell migration, adult hypothalamic structure, and anxiety- and depression-like behaviors sex specifically in mice

胚胎 GABA(B) 受体阻断可改变小鼠的细胞迁移、成人下丘脑结构以及焦虑和抑郁样行为(性别特异性)

Matthew S Stratton, Michelle Staros, Tomaz Budefeld, Brian T Searcy, Connor Nash, Chad Eitel, David Carbone, Robert J Handa, Gregor Majdic, Stuart A Tobet