日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Ubiquitin pathway blockade reveals endogenous ADP-ribosylation marking PARP7 and AHR for degradation.

泛素途径阻断揭示了内源性 ADP 核糖基化标记 PARP7 和 AHR 以进行降解。

Gorelik Andrii, Đukić Nina, Smith Rebecca, Chatrin Chatrin, Suyari Osamu, Matthews Jason, Ahel Ivan

A Myeloid Lineage Signifying Anti-tumor Necrosis Factor Resistance in Crohn's Disease

克罗恩病中髓系细胞谱系提示抗肿瘤坏死因子耐药性

Munasinghe, Sachith; Geem, Duke; Duraiarasan, Kodhai; Maddipatla, Sushma C; Murthy, Shanta; Hwang, Yeonjoo; Pelia, Ranjit S; Anbazhagan, Murugadas; Sharma, Garima; Koti, Vikram; Geiculescu, Irina; Niklinsa-Schirtz, Barbara J; Sauer, Cary; Chinnadurai, Raghavan; Kolachala, Vasantha L; Matthews, Jason D; Kugathasan, Subra

Serglycin modulates inflammation and metabolism in macrophages

Serglycin调节巨噬细胞的炎症和代谢

Porteymour, Shirin; Sajib, Saikat Das; von Hofsten, Susannah; Doncheva, Atanaska I; Bjørnvall, Christina D; Hegge, Beate; Gautier, Mélina; Grujic, Mirjana; Kolan, Pratibha; Krishnan, Karthickeyan Chella; Matthews, Jason; Dalen, Knut T; Pejler, Gunnar; Kolset, Svein O; Knutsen, Erik; Norheim, Frode A

CRISPR screens and quantitative proteomics reveal remodeling of the aryl hydrocarbon receptor-driven proteome through PARP7 activity.

CRISPR 筛选和定量蛋白质组学揭示了通过 PARP7 活性重塑芳烃受体驱动的蛋白质组

Gorelik Andrii, Paulo Joao A, Schroeter Christina B, Lad Melanie, Shurr Abigail, Mastrokalou Chara, Siddiqi Samrah, Suyari Osamu, Brognard John, Walter David, Matthews Jason, Palmer Timothy M, Gygi Steven P, Ahel Ivan

Altered inflammatory mucosal signatures within their spatial and cellular context during active ileal Crohn's disease.

活动性回肠克罗恩病期间,炎症黏膜特征在其空间和细胞环境中发生改变

Kolachala Vasantha L, Maddipatla Sushma Chowdary, Murthy Shanta, Hwang Yeonjoo, Dodd Anne F, Sharma Garima, Munasinghe Sachith, Pelia Ranjit Singh, Venkateswaran Suresh, Anbazhagan Murugadas, Koti Tarun, Jhita Navdeep, Joshi Gaurav N, Lopez Chrissy A, Geem Duke, Yin Hong, Cutler David J, Qiu Peng, Matthews Jason D, Kugathasan Subra

PARP7 and aryl hydrocarbon receptor differentially regulate mammary cancer cell proliferation and STING-induced type I interferon signalling

PARP7和芳烃受体对乳腺癌细胞增殖和STING诱导的I型干扰素信号传导具有不同的调控作用

Olafsen, Ninni E; Åhrling, Samaneh S; Rasmussen, Marit; Erlingsson, Linnea A M; Granly, Emma N; Takaoka, Akinori; Matthews, Jason

Exposure to fine particulate matter in adults is associated with immune cell gene expression related to inflammation, the electron transport chain, and cell cycle regulation

成人暴露于细颗粒物与免疫细胞基因表达有关,这些基因表达与炎症、电子传递链和细胞周期调控相关。

Rundblad, Amanda; Das, Siddhartha; Ginos, Bigina N R; Matthews, Jason; Holven, Kirsten B; Voortman, Trudy; Ulven, Stine M

Metabolic network analysis of Crohn's disease reveals sex- and age-specific cellular phenotypes

克罗恩病代谢网络分析揭示了性别和年龄特异性的细胞表型

Moore, Connor J; Batavia, Mariska; Shao, William; Zulqarnain, Fatima; Kolling, Glynis L; Greene, Adam; Matthews, Jason D; Syed, Sana; Papin, Jason A

Loss of Parp7 increases type I interferon signalling and reduces pancreatic tumour growth by enhancing immune cell infiltration

Parp7 的缺失会增强 I 型干扰素信号传导,并通过增强免疫细胞浸润来抑制胰腺肿瘤的生长。

Kannen, Vinicius; Rasmussen, Marit; Das, Siddhartha; Giuliana, Paolo; Izzati, Fauzia N; Choksi, Hani; Erlingsson, Linnea A M; Olafsen, Ninni E; Åhrling, Samaneh S; Cappello, Paola; Teino, Indrek; Maimets, Toivo; Jaudzems, Kristaps; Gulbinas, Antanas; Dambrauskas, Zilvinas; Edgar, Landon J; Grant, Denis M; Matthews, Jason

Single-cell transcriptomics of rectal organoids from individuals with perianal fistulizing Crohn's disease reveals patient-specific signatures

对患有肛周瘘管型克罗恩病患者的直肠类器官进行单细胞转录组学分析,揭示了患者特异性特征

Murthy, Shanta; Anbazhagan, Murugadas; Maddipatla, Sushma Chowdary; Kolachala, Vasantha L; Dodd, Anne; Pelia, Ranjit; Cutler, David J; Matthews, Jason D; Kugathasan, Subra