日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

A Comparison of Novel Serum Markers of Liver Health in Adolescents With Metabolic Dysfunction-Associated Steatotic Liver Disease.

代谢功能障碍相关脂肪肝病青少年肝脏健康新型血清标志物的比较

期刊:Journal of Cellular and Molecular Medicine
影响因子:4.2
doi:10.1111/jcmm.70817
Bade Neeharika, Hellman Diana A, Matye David J, Jiang Shaoning, Tryggestad Jeanie B, Yu Zhongxin, Short Kevin R, Palle Sirish K
代谢
发表日期：2025
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Bile acid sequestrant inhibits gluconeogenesis via inducing hepatic cysteine dioxygenase type 1 to reduce cysteine availability.

胆汁酸螯合剂通过诱导肝脏半胱氨酸双加氧酶 1 型来抑制糖异生，从而降低半胱氨酸的可用性

期刊:American Journal of Physiology-Gastrointestinal and Liver Physiology
影响因子:3.3
doi:10.1152/ajpgi.00353.2024
Matye David J, Wang Huaiwen, Wang Yifeng, Xiong Lei, Li Tiangang
其它
发表日期：2025
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Hepatocyte and adipocyte CDO1-mediated intracellular cysteine catabolism differentially modulates diet-induced obesity and fatty liver in mice.

肝细胞和脂肪细胞 CDO1 介导的细胞内半胱氨酸分解代谢对小鼠饮食诱导的肥胖和脂肪肝具有不同的调节作用。

期刊:
影响因子:
doi:10.64898/2025.12.05.692669
Chen Jianglei, Clayton Yung-Dai, Du Yanhong, Matye David, Gu Lijie, Hasan Mohammad Nazmul, Li Tiangang
脂肪肝
肥胖
细胞生物学
发表日期：2025
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Cullin 3 RING E3 ligase inactivation causes NRF2-dependent NADH reductive stress, hepatic lipodystrophy, and systemic insulin resistance

Cullin 3 RING E3 连接酶失活会导致 NRF2 依赖性 NADH 还原应激、肝脂肪营养不良和全身性胰岛素抵抗。

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2320934121
Gu, Lijie; Du, Yanhong; Chen, Jianglei; Hasan, Mohammad Nazmul; Clayton, Yung Dai; Matye, David J; Friedman, Jacob E; Li, Tiangang
代谢
NRF2
免疫/内分泌
发表日期：2024
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Deletion of hepatocyte cysteine dioxygenase type 1, a bile acid repressed gene, enhances glutathione synthesis and ameliorates acetaminophen hepatotoxicity

删除肝细胞半胱氨酸双加氧酶 1 型（一种胆汁酸抑制基因）可增强谷胱甘肽合成并减轻对乙酰氨基酚的肝毒性

期刊:Biochemical Pharmacology
影响因子:5.3
doi:10.1016/j.bcp.2024.116103
Jianglei Chen, David Matye, Yung Dai Clayton, Yanhong Du, Mohammad Nazmul Hasan, Lijie Gu, Tiangang Li
细胞生物学
其它细胞
发表日期：2024
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Combining ASBT inhibitor and FGF15 treatments enhances therapeutic efficacy against cholangiopathy in female but not male Cyp2c70 KO mice

联合使用 ASBT 抑制剂和 FGF15 治疗可增强雌性而非雄性 Cyp2c70 KO 小鼠对胆管病的治疗效果

期刊:Journal of Lipid Research
影响因子:5
doi:10.1016/j.jlr.2023.100340
Mohammad Nazmul Hasan, Jianglei Chen, David Matye, Huaiwen Wang, Wenyi Luo, Lijie Gu, Yung Dai Clayton, Yanhong Du, Tiangang Li
信号转导
IHC
发表日期：2023
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TFEB regulates sulfur amino acid and coenzyme A metabolism to support hepatic metabolic adaptation and redox homeostasis

TFEB 调节含硫氨基酸和辅酶 A 代谢，支持肝脏代谢适应和氧化还原稳态

期刊:Nature Communications
影响因子:14.7
doi:10.1038/s41467-022-33465-9
David Matye, Sumedha Gunewardena, Jianglei Chen, Huaiwen Wang, Yifeng Wang, Mohammad Nazmul Hasan, Lijie Gu, Yung Dai Clayton, Yanhong Du, Cheng Chen, Jacob E Friedman, Shelly C Lu, Wen-Xing Ding, Tiangang Li
代谢
IP
WB
TFEB
发表日期：2022
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Effects of apical sodium-bile acid transporter inhibitor and obeticholic acid co-treatment in experimental non-alcoholic steatohepatitis

顶端钠胆汁酸转运体抑制剂与奥贝胆酸联合治疗对实验性非酒精性脂肪性肝炎的影响

期刊:Liver Research
影响因子:2
doi:10.1016/j.livres.2022.11.002
David J Matye, Xuan Qin, Mohammad Nazmul Hasan, Lijie Gu, Yung-Dai Clayton, Feng Li, Tiangang Li
代谢
免疫
肝炎
发表日期：2022
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Cullin neddylation inhibitor attenuates hyperglycemia by enhancing hepatic insulin signaling through insulin receptor substrate stabilization

Cullin Neddylation 抑制剂通过稳定胰岛素受体底物增强肝脏胰岛素信号传导，从而减轻高血糖

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:
doi:10.1073/pnas.2111737119
Cheng Chen, Lijie Gu, David J Matye, Yung-Dai Clayton, Mohammad Nazmul Hasan, Yifeng Wang, Jacob E Friedman, Tiangang Li
信号转导
FCM
IF
IHC-P
WB
Insulin Receptor
FBXW8
发表日期：2022
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Combined ASBT Inhibitor and FGF15 Treatment Improves Therapeutic Efficacy in Experimental Nonalcoholic Steatohepatitis

ASBT 抑制剂与 FGF15 联合治疗可提高实验性非酒精性脂肪性肝炎的治疗效果

期刊:Cellular and Molecular Gastroenterology and Hepatology
影响因子:7.1
doi:10.1016/j.jcmgh.2021.04.013
David J Matye, Huaiwen Wang, Wenyi Luo, Rachel R Sharp, Cheng Chen, Lijie Gu, Kenneth L Jones, Wen-Xing Ding, Jacob E Friedman, Tiangang Li
代谢
免疫
肝炎
发表日期：2021
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