Cullin 3 RING E3 ligase inactivation causes NRF2-dependent NADH reductive stress, hepatic lipodystrophy, and systemic insulin resistance
Cullin 3 RING E3 连接酶失活会导致 NRF2 依赖性 NADH 还原应激、肝脂肪营养不良和全身性胰岛素抵抗。
期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2320934121
Gu, Lijie; Du, Yanhong; Chen, Jianglei; Hasan, Mohammad Nazmul; Clayton, Yung Dai; Matye, David J; Friedman, Jacob E; Li, Tiangang