Topical niclosamide (ATx201) reduces Staphylococcus aureus colonization and increases Shannon diversity of the skin microbiome in atopic dermatitis patients in a randomized, double-blind, placebo-controlled Phase 2 trial
在一项随机、双盲、安慰剂对照的 II 期试验中，局部应用尼克酰胺 (ATx201) 可减少特应性皮炎患者皮肤中金黄色葡萄球菌的定植，并增加皮肤微生物组的香农多样性。
期刊:Clinical and Translational Medicine
影响因子:6.8
doi:10.1002/ctm2.790
Weiss, Anne; Delavenne, Emilie; Matias, Carina; Lagler, Heimo; Simon, Daniel; Li, Ping; Hansen, Jon U; Dos Santos, Teresa Pires; Jana, Bimal; Priemel, Petra; Bangert, Christine; Bauer, Martin; Eberl, Sabine; Nussbaumer-Pröll, Alina; Anne Österreicher, Zoe; Matzneller, Peter; Quint, Tamara; Weber, Maria; Nielsen, Hanne Mørck; Rades, Thomas; Johansen, Helle Krogh; Westh, Henrik; Kim, Wooseong; Mylonakis, Eleftherios; Friis, Christian; Guardabassi, Luca; Pace, John; Lundberg, Carina Vingsbo; M'Zali, Fatima; Butty, Pascal; Sørensen, Nikolaj; Nielsen, Henrik Bjørn; Toft-Kehler, Rasmus; Guttman-Yassky, Emma; Stingl, Georg; Zeitlinger, Markus; Sommer, Morten
