RAF inhibitors promote RAS-RAF interaction by allosterically disrupting RAF autoinhibition
RAF 抑制剂通过变构破坏 RAF 自身抑制来促进 RAS-RAF 相互作用
期刊:Nature Communications
影响因子:14.7
doi:10.1038/s41467-017-01274-0
Ting Jin, Hugo Lavoie, Malha Sahmi, Maud David, Christine Hilt, Amy Hammell, Marc Therrien
