Maurice Madelon M相关文献与解析，生知库

Hepatocellular carcinoma-linked AXIN1 mutations drive low Wnt/β-catenin activity enabling niche-independent growth and YAP/TAZ signaling

Sprangers Joep, Bugter Jeroen M, Xanthakis Despina, Boekhout Michiel, Kok Rutger N U, Geurts Veerle E, Clevers Hans, Brosens Lodewijk A A, Dijk Frederike, RodrÃguez Colman Maria J, van der Vaart Jelte Y, Maurice Madelon M

胰腺癌

肿瘤

发表日期：2026

文献求助收藏

Correction: USP10 drives cancer stemness and enables super-competitor signalling in colorectal cancer

更正：USP10 驱动癌症干细胞特性并促进结直肠癌中的超级竞争者信号传导

期刊:Oncogene

影响因子:7.3

doi:10.1038/s41388-024-03262-3

Reissland, Michaela; Hartmann, Oliver; Tauch, Saskia; Bugter, Jeroen M; Prieto-Garcia, Cristian; Schulte, Clemens; Loebbert, Sinah; Solvie, Daniel; Bitman-Lotan, Eliya; Narain, Ashwin; Jacomin, Anne-Claire; Schuelein-Voelk, Christina; Fuss, Carmina T; Pahor, Nikolett; Ade, Carsten; Buck, Viktoria; Potente, Michael; Li, Vivian; Beliu, Gerti; Wiegering, Armin; Grossmann, Tom; Eilers, Martin; Wolf, Elmar; Maric, Hans; Rosenfeldt, Mathias; Maurice, Madelon M; Dikic, Ivan; Gallant, Peter; Orian, Amir; Diefenbacher, Markus E

BRAF(V600E) augments WNT signaling in colorectal cancer via aberrant DNA methylation.

BRAF(V600E)通过异常DNA甲基化增强结直肠癌中的WNT信号传导

期刊:iScience

影响因子:4.1

doi:10.1016/j.isci.2025.112708

El Bouazzaoui Layla, Bugter Jeroen M, KÃ¼Ã§Ã¼kkÃ¶se Emre, Verheem AndrÃ©, Post Jasmin B, Fenderico Nicola, Borel Rinkes Inne H M, Snippert Hugo J G, Maurice Madelon M, Kranenburg Onno

BRAF(V600E) maintains the CpG island methylator phenotype, and DNA methylation of PRC2 targets genes in colon cancer.

BRAF(V600E) 维持 CpG 岛甲基化表型，PRC2 的 DNA 甲基化靶向结肠癌基因

期刊:iScience

影响因子:4.1

doi:10.1016/j.isci.2025.112905

El Bouazzaoui Layla, Bugter Jeroen M, KÃ¼Ã§Ã¼kkÃ¶se Emre, Verheem AndrÃ©, Post Jasmin B, Fenderico Nicola, Borel Rinkes Inne H M, Snippert Hugo J G, Maurice Madelon M, Kranenburg Onno

WNK kinase regulates plasma membrane levels of the WNT inhibitor RNF43: A WNK-RNF43 circuit regulates WNT signal suppression

WNK激酶调节WNT抑制因子RNF43的质膜水平：WNK-RNF43回路调节WNT信号抑制

期刊:

影响因子:

doi:10.1101/2025.10.08.681128

Colozza, Gabriele; Jordens, Ingrid; Sosa, Eric; Ha, Jeongmin; Sam Wu, Szu-Hsien; Tavernini, Katherina; Català-Bordes, Andrea; Farnhammer, Fiona; Urbán, Noelia; Maurice, Madelon M; Koo, Bon-Kyoung

信号转导

发表日期：2025

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USP10 drives cancer stemness and enables super-competitor signalling in colorectal cancer

USP10 驱动癌症干细胞特性并促进结直肠癌中的超级竞争者信号传导

期刊:Oncogene

影响因子:7.3

doi:10.1038/s41388-024-03141-x

Reissland, Michaela; Hartmann, Oliver; Tauch, Saskia; Bugter, Jeroen M; Prieto-Garcia, Cristian; Schulte, Clemens; Loebbert, Sinah; Solvie, Daniel; Bitman-Lotan, Eliya; Narain, Ashwin; Jacomin, Anne-Claire; Schuelein-Voelk, Christina; Fuss, Carmina T; Pahor, Nikolett; Ade, Carsten; Buck, Viktoria; Potente, Michael; Li, Vivian; Beliu, Gerti; Wiegering, Armin; Grossmann, Tom; Eilers, Martin; Wolf, Elmar; Maric, Hans; Rosenfeldt, Mathias; Maurice, Madelon M; Dikic, Ivan; Gallant, Peter; Orian, Amir; Diefenbacher, Markus E

Organoid-based modeling of intestinal development, regeneration, and repair

基于类器官的肠道发育、再生和修复模型

期刊:Cell Death and Differentiation

影响因子:15.4

doi:10.1038/s41418-020-00665-z

Sprangers, Joep; Zaalberg, Irene C; Maurice, Madelon M

Magical bullets from an indigenous Indian medicinal plant Tinospora cordifolia: An in silico approach for the antidote of SARS-CoV-2

来自印度本土药用植物心叶青牛胆的神奇子弹：SARS-CoV-2 解毒剂的计算机方法

期刊:Proceedings of the National Academy of Sciences of the United States of America

影响因子:9.1

doi:10.1073/pnas.212515399

Schott, Eckart; Bertho, Nicolas; Ge, Qing; Maurice, Madelon M; Ploegh, Hidde L; Thakkar, Sampark S; Shelat, Foram; Thakor, Parth

SARS-CoV-2

发表日期：2021

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Wnt Signaling Directs Neuronal Polarity and Axonal Growth

Wnt信号通路调控神经元极性和轴突生长

期刊:iScience

影响因子:4.1

doi:10.1016/j.isci.2019.02.029

Stanganello, Eliana; Zahavi, Eitan Erez; Burute, Mithila; Smits, Jasper; Jordens, Ingrid; Maurice, Madelon M; Kapitein, Lukas C; Hoogenraad, Casper C

Hepatocellular carcinoma-linked AXIN1 mutations drive low Wnt/β-catenin activity enabling niche-independent growth and YAP/TAZ signaling

与肝细胞癌相关的AXIN1突变导致Wnt/β-catenin活性降低，从而促进细胞在非依赖微环境的生长和YAP/TAZ信号传导。

WNT7B drives a program for pancreatic cancer subtype switching and progression.

WNT7B 驱动胰腺癌亚型转换和进展的程序。

Correction: USP10 drives cancer stemness and enables super-competitor signalling in colorectal cancer

更正：USP10 驱动癌症干细胞特性并促进结直肠癌中的超级竞争者信号传导

BRAF(V600E) augments WNT signaling in colorectal cancer via aberrant DNA methylation.

BRAF(V600E)通过异常DNA甲基化增强结直肠癌中的WNT信号传导

BRAF(V600E) maintains the CpG island methylator phenotype, and DNA methylation of PRC2 targets genes in colon cancer.

BRAF(V600E) 维持 CpG 岛甲基化表型，PRC2 的 DNA 甲基化靶向结肠癌基因

WNK kinase regulates plasma membrane levels of the WNT inhibitor RNF43: A WNK-RNF43 circuit regulates WNT signal suppression

WNK激酶调节WNT抑制因子RNF43的质膜水平：WNK-RNF43回路调节WNT信号抑制

USP10 drives cancer stemness and enables super-competitor signalling in colorectal cancer

USP10 驱动癌症干细胞特性并促进结直肠癌中的超级竞争者信号传导

Organoid-based modeling of intestinal development, regeneration, and repair

基于类器官的肠道发育、再生和修复模型

Magical bullets from an indigenous Indian medicinal plant Tinospora cordifolia: An in silico approach for the antidote of SARS-CoV-2

来自印度本土药用植物心叶青牛胆的神奇子弹：SARS-CoV-2 解毒剂的计算机方法

Wnt Signaling Directs Neuronal Polarity and Axonal Growth

Wnt信号通路调控神经元极性和轴突生长