日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Halofuginone inhibits TGF-β/BMP signaling and in combination with zoledronic acid enhances inhibition of breast cancer bone metastasis

哈洛夫吉酮抑制TGF-β/BMP信号通路,与唑来膦酸联合使用可增强对乳腺癌骨转移的抑制作用。

Juárez, Patricia; Fournier, Pierrick G J; Mohammad, Khalid S; McKenna, Ryan C; Davis, Holly W; Peng, Xiang H; Niewolna, Maria; Mauviel, Alain; Chirgwin, John M; Guise, Theresa A

Analysis of gene expression dynamics revealed delayed and abnormal epidermal repair process in aged compared to young skin

基因表达动态分析显示,与年轻皮肤相比,老年皮肤的表皮修复过程延迟且异常。

Sextius, Peggy; Marionnet, Claire; Tacheau, Charlotte; Bon, François-Xavier; Bastien, Philippe; Mauviel, Alain; Bernard, Bruno A; Bernerd, Françoise; Dubertret, Louis

Insights into the Transforming Growth Factor-β Signaling Pathway in Cutaneous Melanoma

皮肤黑色素瘤中转化生长因子-β信号通路的研究进展

Perrot, Carole Yolande; Javelaud, Delphine; Mauviel, Alain

Expression of microphthalmia-associated transcription factor (MITF), which is critical for melanoma progression, is inhibited by both transcription factor GLI2 and transforming growth factor-β.

小眼畸形相关转录因子(MITF)的表达对于黑色素瘤的进展至关重要,而转录因子 GLI2 和转化生长因子-β 均可抑制MITF的表达

Pierrat Marie-Jeanne, Marsaud Véronique, Mauviel Alain, Javelaud Delphine

TGF-beta-RI kinase inhibitor SD-208 reduces the development and progression of melanoma bone metastases

TGF-β-RI激酶抑制剂SD-208可减少黑色素瘤骨转移的发生和发展

Mohammad, Khalid S; Javelaud, Delphine; Fournier, Pierrick G J; Niewolna, Maria; McKenna, C Ryan; Peng, Xiang H; Duong, Vu; Dunn, Lauren K; Mauviel, Alain; Guise, Theresa A

Increased cAMP levels modulate transforming growth factor-beta/Smad-induced expression of extracellular matrix components and other key fibroblast effector functions.

cAMP 水平升高可调节转化生长因子-β/Smad 诱导的细胞外基质成分表达和其他关键成纤维细胞效应功能

Schiller Meinhard, Dennler Sylviane, Anderegg Ulf, Kokot Agatha, Simon Jan C, Luger Thomas A, Mauviel Alain, Böhm Markus

Transforming growth factor-beta and fibrosis

转化生长因子-β与纤维化

Verrecchia, Franck; Mauviel, Alain

Cytoplasmic SnoN in normal tissues and nonmalignant cells antagonizes TGF-beta signaling by sequestration of the Smad proteins

正常组织和非恶性细胞中的细胞质SnoN通过螯合Smad蛋白来拮抗TGF-β信号通路。

Krakowski, Ariel R; Laboureau, Julien; Mauviel, Alain; Bissell, Mina J; Luo, Kunxin

Distinct involvement of the Jun-N-terminal kinase and NF-kappaB pathways in the repression of the human COL1A2 gene by TNF-alpha

TNF-α抑制人COL1A2基因表达过程中,Jun N端激酶和NF-κB通路发挥着不同的作用

Verrecchia, Franck; Wagner, Erwin F; Mauviel, Alain