日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

LINE1-Mediated Reverse Transcription and Genomic Integration of SARS-CoV-2 mRNA Detected in Virus-Infected but Not in Viral mRNA-Transfected Cells

在病毒感染的细胞中检测到 LINE1 介导的 SARS-CoV-2 mRNA 逆转录和基因组整合,但在病毒 mRNA 转染的细胞中未检测到

Liguo Zhang, Punam Bisht, Anthony Flamier, M Inmaculada Barrasa, Max Friesen, Alexsia Richards, Stephen H Hughes, Rudolf Jaenisch

The dynamic clustering of insulin receptor underlies its signaling and is disrupted in insulin resistance

胰岛素受体的动态聚集是其信号传导的基础,并在胰岛素抵抗中被破坏

Alessandra Dall'Agnese #, Jesse M Platt #, Ming M Zheng, Max Friesen, Giuseppe Dall'Agnese, Alyssa M Blaise, Jessica B Spinelli, Jonathan E Henninger, Erin N Tevonian, Nancy M Hannett, Charalampos Lazaris, Hannah K Drescher, Lea M Bartsch, Henry R Kilgore, Rudolf Jaenisch, Linda G Griffith, Ibrahim

Development of a physiological insulin resistance model in human stem cell-derived adipocytes

人类干细胞衍生脂肪细胞中生理性胰岛素抵抗模型的建立

Max Friesen, Andrew S Khalil, M Inmaculada Barrasa, Jacob F Jeppesen, David J Mooney, Rudolf Jaenisch

Heightened apoptotic priming of vascular cells across tissues and life span predisposes them to cancer therapy-induced toxicities

血管细胞在不同组织和生命周期中凋亡启动增强,使其更容易受到癌症治疗引起的毒性作用的影响。

Johan K E Spetz,Mary H C Florido,Cameron S Fraser,Xingping Qin,Jonathan Choiniere,Stacey J Yu,Rumani Singh,Max Friesen,Lee L Rubin,Joe-Elie Salem,Javid J Moslehi,Kristopher A Sarosiek

SARS-CoV-2 infection of human pluripotent stem cell-derived liver organoids reveals potential mechanisms of liver pathology

SARS-CoV-2 感染人类多能干细胞来源的肝类器官揭示了肝脏病理的潜在机制

Alexsia Richards, Max Friesen, Andrew Khalil, M Inmaculada Barrasa, Lee Gehrke, Rudolf Jaenisch

Patient hiPSCs Identify Vascular Smooth Muscle Arylacetamide Deacetylase as Protective against Atherosclerosis

患者来源的诱导多能干细胞(hiPSCs)鉴定出血管平滑肌芳基乙酰胺脱乙酰酶,该酶对动脉粥样硬化具有保护作用

Takafumi Toyohara ,Filip Roudnicky ,Mary H C Florido ,Toshiaki Nakano ,Haojie Yu ,Shunsuke Katsuki ,Minjin Lee ,Torsten Meissner ,Max Friesen ,Lance S Davidow ,Leon Ptaszek ,Takaaki Abe ,Lee L Rubin ,Alexandre C Pereira ,Masanori Aikawa ,Chad A Cowan

A coagulation defect arising from heterozygous premature termination of tissue factor

因组织因子杂合子过早终止而引起的凝血缺陷

Sol Schulman, Emale El-Darzi, Mary Hc Florido, Max Friesen, Glenn Merrill-Skoloff, Marisa A Brake, Calvin R Schuster, Lin Lin, Randal J Westrick, Chad A Cowan, Robert Flaumenhaft; NIHR BioResource; Willem H Ouwehand, Kathelijne Peerlinck, Kathleen Freson, Ernest Turro, Bruce Furie

Mitoregulin Controls β-Oxidation in Human and Mouse Adipocytes

Mitoregulin 控制人类和小鼠脂肪细胞中的 β-氧化

Max Friesen, Curtis R Warren, Haojie Yu, Takafumi Toyohara, Qiurong Ding, Mary H C Florido, Carolyn Sayre, Benjamin D Pope, Loyal A Goff, John L Rinn, Chad A Cowan

Modeling the Effects of Severe Metabolic Disease by Genome Editing of hPSC-Derived Endothelial Cells Reveals an Inflammatory Phenotype

通过对 hPSC 衍生内皮细胞进行基因组编辑来模拟严重代谢疾病的影响,揭示了炎症表型

Filip Roudnicky, Yanjun Lan, Max Friesen, Gregor Dernick, Jitao David Zhang, Andreas Staempfli, Natalie Bordag, Antje Wagner-Golbs, Klaus Christensen, Martin Ebeling, Martin Graf, Mark Burcin, Claas Aiko Meyer, Chad A Cowan, Christoph Patsch

Activation of IRF1 in Human Adipocytes Leads to Phenotypes Associated with Metabolic Disease

IRF1 在人类脂肪细胞中的激活导致与代谢疾病相关的表型

Max Friesen, Raymond Camahort, Youn-Kyoung Lee, Fang Xia, Robert E Gerszten, Eugene P Rhee, Rahul C Deo, Chad A Cowan