日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Deletions in VANGL1 are a risk factor for antibody-mediated kidney disease

VANGL1 缺失是抗体介导肾脏疾病的风险因素

Simon H Jiang, Sevcan Mercan, Ilenia Papa, Max Moldovan, Giles D Walters, Mark Koina, Mitali Fadia, Maurice Stanley, Tom Lea-Henry, Amelia Cook, Julia Ellyard, Brendan McMorran, Madhivanan Sundaram, Russell Thomson, Pablo F Canete, Wendy Hoy, Holly Hutton, Monika Srivastava, Kathryn McKeon, Iñigo de

A feedback loop between the androgen receptor and 6-phosphogluoconate dehydrogenase (6PGD) drives prostate cancer growth

雄激素受体和 6-磷酸葡萄糖酸脱氢酶 (6PGD) 之间的反馈回路驱动前列腺癌的生长

Joanna L Gillis, Josephine A Hinneh, Natalie K Ryan, Swati Irani, Max Moldovan, Lake-Ee Quek, Raj K Shrestha, Adrienne R Hanson, Jianling Xie, Andrew J Hoy, Jeff Holst, Margaret M Centenera, Ian G Mills, David J Lynn, Luke A Selth, Lisa M Butler

Human DECR1 is an androgen-repressed survival factor that regulates PUFA oxidation to protect prostate tumor cells from ferroptosis

人类 DECR1 是一种雄激素抑制的生存因子,可调节 PUFA 氧化以保护前列腺肿瘤细胞免于铁死亡

Zeyad D Nassar #, Chui Yan Mah #, Jonas Dehairs, Ingrid Jg Burvenich, Swati Irani, Margaret M Centenera, Madison Helm, Raj K Shrestha, Max Moldovan, Anthony S Don, Jeff Holst, Andrew M Scott, Lisa G Horvath, David J Lynn, Luke A Selth, Andrew J Hoy, Johannes V Swinnen, Lisa M Butler

Transcriptional and metabolic rewiring of colorectal cancer cells expressing the oncogenic KRASG13D mutation

表达致癌 KRASG13D 突变的结肠直肠癌细胞的转录和代谢重组

Theodosia Charitou, Sriganesh Srihari, Miriam A Lynn, Mohamed-Ali Jarboui, Erik Fasterius, Max Moldovan, Senji Shirasawa, Toshiyuki Tsunoda, Marius Ueffing, Jianling Xie, Jin Xin, Xuemin Wang, Christopher G Proud, Karsten Boldt, Cristina Al-Khalili Szigyarto, Walter Kolch, David J Lynn

Identification of Novel Response and Predictive Biomarkers to Hsp90 Inhibitors Through Proteomic Profiling of Patient-derived Prostate Tumor Explants

通过对患者前列腺肿瘤外植体的蛋白质组学分析来鉴定 Hsp90 抑制剂的新反应和预测生物标志物

Elizabeth V Nguyen, Margaret M Centenera, Max Moldovan, Rajdeep Das, Swati Irani, Andrew D Vincent, Howard Chan, Lisa G Horvath, David J Lynn, Roger J Daly, Lisa M Butler

Dysregulated fibronectin trafficking by Hsp90 inhibition restricts prostate cancer cell invasion

Hsp90 抑制导致纤连蛋白运输失调,限制前列腺癌细胞侵袭

Heather K Armstrong, Joanna L Gillis, Ian R D Johnson, Zeyad D Nassar, Max Moldovan, Claire Levrier, Martin C Sadowski, Mei Yieng Chin, Emma S Tomlinson Guns, Gerard Tarulli, David J Lynn, Douglas A Brooks, Luke A Selth, Margaret M Centenera, Lisa M Butler