日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Molecular assessment of intratumoral immune cell subsets and potential mechanisms of resistance to odronextamab, a CD20×CD3 bispecific antibody, in patients with relapsed/refractory B-cell non-Hodgkin lymphoma

复发/难治性 B 细胞非霍奇金淋巴瘤患者肿瘤内免疫细胞亚群的分子评估及其对 CD20×CD3 双特异性抗体 odronextamab 的潜在耐药机制

Jurriaan Brouwer-Visser, Nathalie Fiaschi, Raquel P Deering, Kamil J Cygan, Darius Scott, Se Jeong, Lauren Boucher, Namita T Gupta, Suraj Gupta, Christina Adler, Max S Topp, Rajat Bannerji, Johannes Duell, Ranjana H Advani, Dina M Flink, Aafia Chaudhry, Gavin Thurston, Srikanth R Ambati, Vladimir Ja

Three-Year Follow-Up of KTE-X19 in Patients With Relapsed/Refractory Mantle Cell Lymphoma, Including High-Risk Subgroups, in the ZUMA-2 Study

ZUMA-2 研究中对复发/难治性套细胞淋巴瘤患者(包括高风险亚组)进行 KTE-X19 的三年随访

Michael Wang, Javier Munoz, Andre Goy, Frederick L Locke, Caron A Jacobson, Brian T Hill, John M Timmerman, Houston Holmes, Samantha Jaglowski, Ian W Flinn, Peter A McSweeney, David B Miklos, John M Pagel, Marie José Kersten, Krimo Bouabdallah, Rashmi Khanal, Max S Topp, Roch Houot, Amer Beitinjaneh

Homozygous BCMA gene deletion in response to anti-BCMA CAR T cells in a patient with multiple myeloma

多发性骨髓瘤患者对抗 BCMA CAR T 细胞产生纯合 BCMA 基因缺失反应

Matteo C Da Vià, Oliver Dietrich, Marietta Truger, Panagiota Arampatzi, Johannes Duell, Anke Heidemeier, Xiang Zhou, Sophia Danhof, Sabrina Kraus, Manik Chatterjee, Manja Meggendorfer, Sven Twardziok, Maria-Elisabeth Goebeler, Max S Topp, Michael Hudecek, Sabrina Prommersberger, Kristen Hege, Shari

Single- and double-hit events in genes encoding immune targets before and after T cell-engaging antibody therapy in MM

多发性骨髓瘤患者接受 T 细胞介导抗体治疗之前和之后免疫靶标基因的单击和双击事件

Marietta S Truger, Johannes Duell, Xiang Zhou, Larissa Heimeshoff, Anna Ruckdeschel, Mara John, Angela Riedel, Sebastian Hüper, Jessica Peter, Wencke Walter, Larissa Haertle, Manja Meggendorfer, Max S Topp, Andreas Rosenwald, Matteo Claudio Da Via, Niccolo Bolli, Niels Weinhold, Hermann Einsele, Cla

Changes in clinical laboratory parameters and pharmacodynamic markers in response to blinatumomab treatment of patients with relapsed/refractory ALL

复发/难治性 ALL 患者接受 Blinatumomab 治疗后临床实验室参数和药效学标志物的变化

Virginie Nägele #, Andrea Kratzer #, Gerhard Zugmaier, Chris Holland, Youssef Hijazi, Max S Topp, Nicola Gökbuget, Patrick A Baeuerle, Peter Kufer, Andreas Wolf, Matthias Klinger

Combined PI3K/Akt and Hsp90 targeting synergistically suppresses essential functions of alloreactive T cells and increases Tregs

PI3K/Akt 和 Hsp90 联合靶向可协同抑制同种反应性 T 细胞的基本功能并增加 Treg

Carsten Berges, Tanja Bedke, Claudia Stuehler, Nina Khanna, Sarah Zehnter, Michaela Kruhm, Nadine Winter, Ralf C Bargou, Max S Topp, Hermann Einsele, Manik Chatterjee

Distinct and complementary roles for Aspergillus fumigatus-specific Tr1 and Foxp3+ regulatory T cells in humans and mice

烟曲霉特异性 Tr1 和 Foxp3+ 调节性 T 细胞在人类和小鼠中发挥着独特且互补的作用

Tanja Bedke, Rossana G Iannitti, Antonella De Luca, Gloria Giovannini, Francesca Fallarino, Carsten Berges, Jean-Paul Latgé, Hermann Einsele, Luigina Romani, Max S Topp

Selective depletion of alloreactive T cells by targeted therapy of heat shock protein 90: a novel strategy for control of graft-versus-host disease

通过热休克蛋白 90 的靶向治疗选择性地消除同种反应性 T 细胞:一种控制移植物抗宿主病的新策略

Claudia Stuehler, Stephan Mielke, Manik Chatterjee, Johannes Duell, Sarah Lurati, Florian Rueckert, Hermann Einsele, Ralf C Bargou, Max S Topp

Restoration of CD28 expression in CD28- CD8+ memory effector T cells reconstitutes antigen-induced IL-2 production

CD28-CD8+记忆效应T细胞中CD28表达的恢复重建了抗原诱导的IL-2产生

Max S Topp, Stanley R Riddell, Yoshiki Akatsuka, Michael C Jensen, Joseph N Blattman, Philip D Greenberg