16p11.2 deletion is associated with hyperactivation of human iPSC-derived dopaminergic neuron networks and is rescued by RHOA inhibition in vitro
16p11.2 缺失与人类 iPSC 衍生的多巴胺能神经元网络过度活跃有关,可通过体外 RHOA 抑制来挽救
期刊:Nature Communications
影响因子:14.7
doi:10.1038/s41467-021-23113-z
Maria Sundberg, Hannah Pinson #, Richard S Smith #, Kellen D Winden, Pooja Venugopal, Derek J C Tai, James F Gusella, Michael E Talkowski, Christopher A Walsh, Max Tegmark, Mustafa Sahin