日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Design, Synthesis, and Characterization of HBP-Vectorized Methotrexate Prodrug Molecule 1102-39: Evaluation of In Vitro Cytotoxicity Activity in Cell Culture Models, Preliminary In Vivo Safety and Efficacy Results in Rodents

HBP 载体化甲氨蝶呤前药分子 1102-39 的设计、合成和表征:在细胞培养模型中评估体外细胞毒性活性,在啮齿动物中初步的体内安全性和有效性结果

Maxim Egorov, Jean-Yves Goujon, Marie Sicard, Christelle Moal, Samuel Pairel, Ronan Le Bot

mTOR Inhibition via Displacement of Phosphatidic Acid Induces Enhanced Cytotoxicity Specifically in Cancer Cells

通过置换磷脂酸来抑制 mTOR 可增强癌细胞的细胞毒性

Tra-Ly Nguyen, Marie-Julie Nokin, Maxim Egorov, Mercedes Tomé, Clément Bodineau, Carmelo Di Primo, Lætitia Minder, Joanna Wdzieczak-Bakala, Maria Concepcion Garcia-Alvarez, Jérôme Bignon, Odile Thoison, Bernard Delpech, Georgiana Surpateanu, Yves-Michel Frapart, Fabienne Peyrot, Kahina Abbas, Silvia