日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Integrating collecting systems in human kidney organoids through fusion of distal nephron to ureteric bud.

通过将远端肾单位与输尿管芽融合,在人类肾脏类器官中整合集合系统

Shi Min, Crouse Brittney, Sundaram Nambirajan, Pode Shakked Naomi, Thorner Konrad, King Nathaniel M, Dutta Parna, Ester Lioba, Zhang Weitao, Govindarajah Vinothini, Kopan Raphael, Cebrian Cristina, Mayhew Christopher N, Helmrath Michael A, Bonventre Joseph V, McCracken Kyle W

Pioneer and PRDM transcription factors coordinate bivalent epigenetic states to safeguard cell fate

Pioneer 和 PRDM 转录因子协调二价表观遗传状态,以保障细胞命运

Matsui, Satoshi; Granitto, Marissa; Buckley, Morgan; Ludwig, Katie; Koigi, Sandra; Shiley, Joseph; Zacharias, William J; Mayhew, Christopher N; Lim, Hee-Woong; Iwafuchi, Makiko

Protocol for establishing inducible CRISPR interference system for multiple-gene silencing in human pluripotent stem cells

建立可诱导CRISPR干扰系统以实现人类多能干细胞多基因沉默的方案

Matsui, Satoshi; Shiley, Joseph R; Granitto, Marissa; Ludwig, Katie; Buckley, Morgan; Koigi, Sandra; Mirizio, Gerardo; Hu, Yueh-Chiang; Mayhew, Christopher N; Iwafuchi, Makiko

Patient-Specific Midbrain Organoids with CRISPR Correction Reveal Disease Mechanisms and Enable Therapeutic Evaluation in Neuronopathic Gaucher Disease

利用 CRISPR 技术进行基因编辑的患者特异性中脑类器官揭示了神经病变型戈谢病的疾病机制,并可用于治疗评估。

Lin, Yi; Liou, Benjamin; Fannin, Venette; Adler, Stuart; Mayhew, Christopher N; Hammonds, Jason E; Hu, Yueh-Chiang; Tchieu, Jason; Zhang, Wujuan; Zhao, Xueheng; Beres, Rebecca L; Setchell, Kenneth Dr; Kaynak, Ahmet; Qi, Xiaoyang; Feldman, Ricardo A; Sun, Ying

Engineering Large-Scale and Innervated Functional Human Gut for Transplantation

构建用于移植的大规模、神经支配的功能性人类肠道

Poling, Holly M; Noël, Théo; Singh, Akaljot; Fisher, Garrett W; Thorner, Konrad; Chaturvedi, Praneet; Nattamai, Kalpana; Srivastava, Kalpana; Batie, Matthew R; Hausfeld, Taylor; Pitstick, Amy L; Ménoret, Séverine; Anegon, Ignacio; Barrile, Riccardo; Mayhew, Christopher N; Takebe, Takanori; Wells, James M; Helmrath, Michael A; Mahe, Maxime M

Digitalized Human Organoid for Wireless Phenotyping

用于无线表型分析的数字化人体类器官

Kimura, Masaki; Azuma, Momoko; Zhang, Ran-Ran; Thompson, Wendy; Mayhew, Christopher N; Takebe, Takanori

Dynamic transcriptional and epigenomic reprogramming from pediatric nasal epithelial cells to induced pluripotent stem cells

从儿童鼻上皮细胞到诱导多能干细胞的动态转录和表观基因组重编程

Ji, Hong; Zhang, Xue; Oh, Sunghee; Mayhew, Christopher N; Ulm, Ashley; Somineni, Hari K; Ericksen, Mark; Wells, James M; Khurana Hershey, Gurjit K

RB tumor suppressive function in response to xenobiotic hepatocarcinogens

RB在应对外源性肝致癌物时发挥抑癌功能

Reed, Christopher; Hutcheson, Jack; Mayhew, Christopher N; Witkiewicz, Agnieszka K; Knudsen, Erik S

RB and p53 cooperate to prevent liver tumorigenesis in response to tissue damage

RB和p53协同作用,防止肝脏组织损伤后发生肿瘤。

McClendon, A Kathleen; Dean, Jeffry L; Ertel, Adam; Fu, Zhiyan; Rivadeneira, Dayana B; Reed, Christopher A; Bourgo, Ryan J; Witkiewicz, Agnieszka; Addya, Sankar; Mayhew, Christopher N; Grimes, H Leighton; Fortina, Paolo; Knudsen, Erik S

Converting human pluripotent stem cells into beta-cells: recent advances and future challenges

将人类多能干细胞转化为β细胞:最新进展与未来挑战

Mayhew, Christopher N; Wells, James M