日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

LYMTACs:chimeric small molecules repurpose lysosomal membrane proteins for target protein relocalization and degradation.

LYMTACs:嵌合小分子可重新利用溶酶体膜蛋白,实现靶蛋白的重新定位和降解

Nalawansha Dhanusha A, Mazis Georgios, Husemoen Gitte, Ashton Kate S, Deng Weixian, Wurz Ryan P, Tran Anh T, Lanman Brian A, Xie Jiansong, Guenette Robert G, Li Shiqian, Smith Christopher E, Archunan Suresh, Agnihotram Manoj K, Sadhukhan Arghya, Kapoor Rajiv, Wilde Chris, Koirala Sajjan, De Sousa E Melo Felipe, Potts Patrick Ryan

Discovery of (R)-2-amino-3-triazolpropanoic acid derivatives as NMDA receptor glycine site agonists with GluN2 subunit-specific activity

发现(R)-2-氨基-3-三唑丙酸衍生物作为NMDA受体甘氨酸位点激动剂,具有GluN2亚基特异性活性

Zhao, Fabao; Mazis, Georgios; Yi, Feng; Lotti, James S; Layeux, Michael S; Schultz, Eric P; Bunch, Lennart; Hansen, Kasper B; Clausen, Rasmus P