日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Integrated computational and experimental immunoengineering of adeno-associated virus capsid T cell epitopes in mice.

小鼠腺相关病毒衣壳T细胞表位的综合计算和实验免疫工程。

Bing Sojin, Eskandarian Arya, Smith Sean, Sajib Abdul Mohin, Warrington Stephanee, Saleh Sima, Najera Susana S, J D'Esposito Rebecca, Santana-Quintero Luis, Mazor Ronit

AAV2 delivery of the saCas9 gene results in presentation of an HLA-A(∗)02:01-restricted T cell epitope potent to induce T cell cytotoxicity.

AAV2 递送 saCas9 基因可导致 HLA-A(∗)02:01 限制性 T 细胞表位的呈现,该表位可有效诱导 T 细胞毒性

Najera Susana S, Nicastri Annalisa, Bing Sojin, Sajib Abdul Mohin, Ternette Nicola, Mazor Ronit

Low cross reactivity between wild type and deamidated AAV can lead to false negative results in immune monitoring T-cell assays

野生型和脱酰胺型AAV之间的低交叉反应性可能导致免疫监测T细胞检测出现假阴性结果。

Bing, So Jin; Warrington, Stephanee; Mazor, Ronit

Immunodominant Linear B-Cell Epitopes of SARS-CoV-2 Spike, Identified by Sera from K18-hACE2 Mice Infected with the WT or Variant Viruses

通过感染野生型或变异病毒的 K18-hACE2 小鼠血清鉴定出的 SARS-CoV-2 刺突的免疫显性线性 B 细胞表位

Yinon Levy, Ron Alcalay, Anat Zvi, Efi Makdasi, Eldar Peretz, Tal Noy-Porat, Theodor Chitlaru, Michal Mandelboim, Ohad Mazor, Ronit Rosenfeld

In vivo pharmacokinetic enhancement of monomeric Fc and monovalent bispecific designs through structural guidance

通过结构指导实现单体Fc和单价双特异性抗体设计的体内药代动力学增强

Shan, Lu; Dyk, Nydia Van; Haskins, Nantaporn; Cook, Kimberly M; Rosenthal, Kim L; Mazor, Ronit; Dragulin-Otto, Sonia; Jiang, Yu; Wu, Herren; Dall'Acqua, William F; Borrok, Martin J; Damschroder, Melissa M; Oganesyan, Vaheh

Improving the In Vivo Efficacy of an Anti-Tac (CD25) Immunotoxin by Pseudomonas Exotoxin A Domain II Engineering

利用铜绿假单胞菌外毒素A结构域II工程改造提高抗Tac(CD25)免疫毒素的体内疗效

Kaplan, Gilad; Mazor, Ronit; Lee, Fred; Jang, Youjin; Leshem, Yasmin; Pastan, Ira

Strategies to Reduce the Immunogenicity of Recombinant Immunotoxins

降低重组免疫毒素免疫原性的策略

Mazor, Ronit; King, Emily M; Pastan, Ira

Low-Dose Methotrexate Prevents Primary and Secondary Humoral Immune Responses and Induces Immune Tolerance to a Recombinant Immunotoxin

低剂量甲氨蝶呤可抑制原发性和继发性体液免疫反应,并诱导对重组免疫毒素的免疫耐受。

King, Emily M; Mazor, Ronit; Çuburu, Nicolas; Pastan, Ira

Anti-drug antibodies to LMB-100 are enhanced by mAbs targeting OX40 and CTLA4 but not by mAbs targeting PD1 or PDL-1

针对LMB-100的抗药物抗体可被靶向OX40和CTLA4的单克隆抗体增强,但不能被靶向PD1或PDL-1的单克隆抗体增强。

Mazor, Ronit; King, Emily; Pastan, Ira

Rational design of low immunogenic anti CD25 recombinant immunotoxin for T cell malignancies by elimination of T cell epitopes in PE38

通过消除PE38中的T细胞表位,合理设计用于治疗T细胞恶性肿瘤的低免疫原性抗CD25重组免疫毒素

Mazor, Ronit; Kaplan, Gilad; Park, Dong; Jang, Youjin; Lee, Fred; Kreitman, Robert; Pastan, Ira