日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Biomolecular Condensates as Emerging Biomaterials: Functional Mechanisms and Advances in Computational and Experimental Approaches

生物分子凝聚体作为新兴生物材料:功能机制及计算和实验方法的进展

Zhu, Qiang; Raza, Zahra; Do-Ha, Dzung; De Costa, Emma; Sasheva, Pavlina; McAlary, Luke; Mahmodi, Hadi; Bowen, Warwick P; Ooi, Lezanne; Kabakova, Irina; Yu, Haibo

Development of a targeted BioPROTAC degrader selective for misfolded SOD1

开发一种针对错误折叠的SOD1的靶向BioPROTAC降解剂

Chisholm, Christen G; Bartlett, Rachael; Brown, Mikayla L; Proctor, Emma-Jayne; Farrawell, Natalie E; Gorman, Jody; Delerue, Fabien; Ittner, Lars M; Vine-Perrow, Kara L; Ecroyd, Heath; Cashman, Neil R; Saunders, Darren N; McAlary, Luke; Lum, Jeremy S; Yerbury, Justin J

Subcellular mass spectrometry imaging of lipids and nucleotides using transmission geometry ambient laser desorption and plasma ionisation

利用透射几何环境激光解吸和等离子体电离技术对脂质和核苷酸进行亚细胞质谱成像

Young, Reuben S E; Piper, Ann-Katrin; McAlary, Luke; McKinnon, Jayden C; Lum, Jeremy S; Soltwisch, Jens; Niehaus, Marcel; Ellis, Shane R

A polytherapy approach demonstrates therapeutic efficacy for the treatment of SOD1 associated amyotrophic lateral sclerosis.

多药联合疗法对治疗 SOD1 相关肌萎缩侧索硬化症具有疗效

Lum Jeremy S, Brown Mikayla L, Farrawell Natalie E, Bartlett Rachael, Chisholm Christen G, Gorman Jody, Dosseto Anthony, Dux Florian, McInnes Lachlan E, Ecroyd Heath, McAlary Luke, Crouch Peter J, Donnelly Paul S, Yerbury Justin J

Spatial Organisation and Invasive Behaviour of Metastatic Cutaneous Squamous Cell Carcinoma-Derived Multicellular Spheroids Reflect Tumour Cell Phenotype.

转移性皮肤鳞状细胞癌衍生的多细胞球体的空间组织和侵袭行为反映了肿瘤细胞表型。

Genenger Benjamin, Conley Jessica, Penney Chelsea, McAlary Luke, Perry Jay R, Ashford Bruce, Ranson Marie

Amyotrophic Lateral Sclerosis: Proteins, Proteostasis, Prions, and Promises

肌萎缩侧索硬化症:蛋白质、蛋白质稳态、朊病毒和希望

McAlary, Luke; Chew, Yee Lian; Lum, Jeremy Stephen; Geraghty, Nicholas John; Yerbury, Justin John; Cashman, Neil R

Emerging Developments in Targeting Proteotoxicity in Neurodegenerative Diseases

神经退行性疾病中靶向蛋白毒性的最新进展

McAlary, Luke; Plotkin, Steven S; Cashman, Neil R

Prion-Like Propagation of Protein Misfolding and Aggregation in Amyotrophic Lateral Sclerosis

肌萎缩侧索硬化症中蛋白质错误折叠和聚集的朊病毒样传播

McAlary, Luke; Plotkin, Steven S; Yerbury, Justin J; Cashman, Neil R

Corrigendum: Prion-Like Propagation of Protein Misfolding and Aggregation in Amyotrophic Lateral Sclerosis

更正:肌萎缩侧索硬化症中蛋白质错误折叠和聚集的朊病毒样传播

McAlary, Luke; Plotkin, Steven S; Yerbury, Justin J; Cashman, Neil R

Tryptophan 32-mediated SOD1 aggregation is attenuated by pyrimidine-like compounds in living cells

在活细胞中,嘧啶类化合物可减弱色氨酸32介导的SOD1聚集。

Pokrishevsky, Edward; McAlary, Luke; Farrawell, Natalie E; Zhao, Beibei; Sher, Mine; Yerbury, Justin J; Cashman, Neil R