Nanoparticle-formulated mRNA encoding engineered multivalent SIRPα-Fc fusion proteins shows robust anti-cancer activity in preclinical models.
纳米颗粒制剂的 mRNA 编码工程化的多价 SIRPα-Fc 融合蛋白在临床前模型中显示出强大的抗癌活性
期刊:Molecular Therapy-Nucleic Acids
影响因子:6.1
doi:10.1016/j.omtn.2025.102550
Lal Shruti, Sallets Adrienne, Bandi Srinivasa R, Adusumilli Gowrisudha, Liu Weiqun, Low Ray, Ferry Kimmy, MacDonough Chris, ElAzzouny Mahmoud, Haabeth Ole A W, McKinlay Colin J, Hsu Pei-Ken, Sharma Anushtha, Dhungel Pragyesh, Triplett Jenna, Leong Meredith, McCartney-Melstad Evan, Deutsch Samuel, Gunasekaran Kannan
