日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

In vivo mapping of protein-protein interactions of schizophrenia risk factors generates an interconnected disease network

通过对精神分裂症风险因素的蛋白质-蛋白质相互作用进行体内定位,可以构建一个相互关联的疾病网络。

McClatchy, Daniel B; Lane, Jeff; Powell, Susan B; Yates Iii, John R

Mutant prion protein enhances NMDA receptor activity, activates PKC, and triggers rapid excitotoxicity in mice

突变朊病毒蛋白增强NMDA受体活性,激活蛋白激酶C (PKC),并在小鼠中引发快速兴奋性毒性。

Lin, Joie; Callender, Julia A; Mayfield, Joshua E; McClatchy, Daniel B; Ojeda-Juárez, Daniel; Pourhamzeh, Mahsa; Soldau, Katrin; Kurt, Timothy D; Danque, Garrett A; Khuu, Helen; Ronson, Josephina E; Pizzo, Donald P; Du, Yixing; Gruber, Maxwell A; Sevillano, Alejandro M; Wang, Jin; Orrú, Christina D; Chen, Joy; Funk, Gail; Aguilar-Calvo, Patricia; Aulston, Brent D; Roy, Subhojit; Rho, Jong M; Bui, Jack D; Newton, Alexandra C; Lipton, Stuart A; Caughey, Byron; Patrick, Gentry N; Doré, Kim; Yates, John R 3rd; Sigurdson, Christina J

Insights into Free Drug Release from Efficacious N-Acyl O-Aminophenol Duocarmycin Prodrugs.

对高效N-酰基O-氨基苯酚杜卡霉素前药的游离药物释放的深入研究

Chakraborty Nilanjana, Momirov Jelena, Radakovic Aleksandar, Chatterjee Shreyosree, Kirchhoff Aaron M, Kolb Anna-Lena, West Thomas J, Sanchez Brittany B, Martinez-Bartolome Salvador, Saviola Anthony, McClatchy Daniel, Yates John R 3rd, Chen Jason S, Lairson Luke L, Felding Brunie H, Boger Dale L

PrP (C) -induced signaling in human neurons activates phospholipase Cɣ1 and an Arc/Arg3.1 response

PrP(C)诱导的人类神经元信号传导激活磷脂酶Cγ1和Arc/Arg3.1反应

Ojeda-Juarez, Daniel; Funk, Gail; Richards, Emily; Rajic, Alexander J; McClatchy, Daniel B; Soldau, Katrin; Chen, Xu; Yates, John R; Gonias, Steven L; Sigurdson, Christina J

Using in vivo intact structure for system-wide quantitative analysis of changes in proteins

利用体内完整结构对蛋白质变化进行系统性定量分析

Son, Ahrum; Kim, Hyunsoo; Diedrich, Jolene K; Bamberger, Casimir; McClatchy, Daniel B; Lipton, Stuart A; Yates, John R

Single‐cell spatial and non‐spatial RNA sequencing on herpes simplex virus 1 (HSV‐1) infected 2D and 3D cerebral organoids reveal molecular granularity on virus‐human gene interactions in Alzheimer’s disease

对单纯疱疹病毒1型(HSV-1)感染的二维和三维脑类器官进行单细胞空间和非空间RNA测序,揭示了阿尔茨海默病中病毒-人类基因相互作用的分子精细性

Barajas, Jonathan; Yang, Zhi; Agyare, Edward; Zhu, Xueyou; Yoon, Saun-Joo; Han, Bo; McClatchy, Daniel B; Labra, Sergio R; Baal, Christine; Lipton, Stuart A; Yates, John R III; Dawes, Pepper; Barton, Nathaniel J; Orszulak, Adrian R; Chigas, Samantha M; Tran, Khanh; Sundstrom, Jonathan; Olson, Meagan N; Murray, Liam F; Oh, HyungSuk; Church, George M; Knipe, David M; Readhead, Benjamin; Chan, Yingleong; Lim, Elaine T

Acid Cleavable Biotin-Alkyne Improves Sensitivity for Direct Detection of Biotin Labeled Peptides in Biorthogonal Noncanonical Amino Acid Tagging Analysis.

酸可裂解生物素-炔烃提高了生物正交非天然氨基酸标记分析中生物素标记肽直接检测的灵敏度

McClatchy Daniel B, Garrett Patrick T, Jung Titus, Diedrich Jolene K, Yates John R 3rd

Quantitative analysis of proteostasis networks: are there applications for dementia?

蛋白质稳态网络的定量分析:在痴呆症治疗中是否有应用?

McClatchy, Daniel B

Acid cleavable biotin-alkyne improves sensitivity for direct detection of biotin labeled peptides in BONCAT analysis.

酸可裂解生物素-炔烃提高了BONCAT分析中直接检测生物素标记肽的灵敏度

McClatchy Daniel B, Yates John R 3rd

Native top-down proteomics reveals EGFR-ERα signaling crosstalk in breast cancer cells dissociates NUTF2 dimers to modulate ERα signaling and cell growth

自上而下的蛋白质组学研究揭示了乳腺癌细胞中EGFR-ERα信号通路相互作用,该相互作用通过解离NUTF2二聚体来调节ERα信号通路和细胞生长。

Yates, John 3rd; Gomes, Fabio; Durbin, Kenneth; Schauer, Kevin; Nwachukwu, Jerome; Russo, Robin; Njeri, Jacqline; Saviola, Anthony; McClatchy, Daniel; Diedrich, Jolene; Garrett, Patrick; Papa, Alexandra; Ciolacu, Ianis; Kelleher, Neil; Nettles, Kendall