日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A polygenetic rat model of divergent aerobic capacity reveals a liver-brain interaction impacting Alzheimer's disease-like phenotypes

具有不同有氧能力的多基因大鼠模型揭示了肝脑相互作用对阿尔茨海默病样表型的影响

Lysaker, Colton R; Kugler, Benjamin A; Csikos, Vivien; Birky, Cole J; Gilmore, Caleb A; Wenger, Madi; Franczak, Edziu; Davis, Xin; Hauger, Brittany M; Allen, Julie A; Troutwine, Benjamin R; Gonzalez-Duran, Laura; McCoin, Colin S; Chauhan, Munish; Harris, Janna L; Frazier, Alexandria L; Winter, Michelle K; Koch, Lauren G; Britton, Steven L; Thyfault, John P; Wilkins, Heather M

APOE4 Exerts Partial Diet-dependent Effects on Energy Expenditure and Skeletal Muscle Mitochondrial Pathways in a Preclinical Model.

在临床前模型中,APOE4 对能量消耗和骨骼肌线粒体通路产生部分饮食依赖性影响

Johnson Chelsea N, Lysaker Colton R, Gast Elaine C, McCoin Colin S, Kemna Riley E, Fuller Kelly N Z, Kugler Benjamin A, Franczak Edziu, Csikos Vivien, Allen Julie, John Casey S, Wolf MaryJane A, Morris Matthew E, Thyfault John P, Wilkins Heather M, Geiger Paige C, Morris Jill K

Donepezil treatment, alone or combined with exercise, enhances skeletal muscle function in healthy and advanced aging disease mouse models.

多奈哌齐治疗,无论是单独使用还是与运动结合使用,都能增强健康和衰老疾病小鼠模型的骨骼肌功能。

Ernst Nicholas J, Franczak Edziu, Allen Julie, Minchew Everett C, Readyoff Andrew T, Farlow Miles C, Spangenburg Espen E, Miller Benjamin F, Morris Jill K, Shankar Kartik, Sardiu Mihaela E, Zhu Hao, Stanford John A, Thyfault John P, McCoin Colin S

Loss of ovarian function prevents exercise-induced activation of hepatic mitophagic flux.

卵巢功能丧失会阻止运动诱导的肝脏线粒体自噬通量的激活

Franczak Edziu, Kugler Benjamin A, Salathe Sebastian F, Allen Julie A, Sardiu Mihaela E, McCoin Colin S, Hevener Andrea L, Morris E Matthew, Thyfault John P

Hepatic ketogenic insufficiency blunts exercise-induced energy expenditure and alters mitochondrial proteins in skeletal muscle

肝脏生酮功能不足会减弱运动引起的能量消耗,并改变骨骼肌中的线粒体蛋白。

Davis, Xin C; McCoin, Colin S; Salathe, Sebastian F; Franczak, Edziu; Allen, Julie A; Queathem, Eric D; Fulghum, Kyle L; Puchalska, Patrycja; Crawford, Peter A; Thyfault, John P; Morris, E Matthew

Proteomic and metabolic profiling reveals APOE4-dependent shifts in whole brain, neuronal, and astrocytic mitochondrial function and glycolysis.

蛋白质组学和代谢组学分析揭示了 APOE4 依赖性的全脑、神经元和星形胶质细胞线粒体功能和糖酵解的变化

Lysaker Colton R, Johnson Chelsea N, Csikos Vivien, Franczak Edziu, Benson Maggie, Gilmore Caleb A, Birky Cole J, Davis Xin, McCoin Colin S, Smith Keith P, Puchalska Patrycja, Crawford Peter, Slawson Chad, Thyfault John P, Geiger Paige C, Morris Jill K, Wilkins Heather M

Sex and BNIP3 genotype, rather than acute lipid injection, modulate hepatic mitochondrial function and steatosis risk in mice

性别和BNIP3基因型,而非急性脂质注射,可调节小鼠肝脏线粒体功能和脂肪变性风险。

Fuller, Kelly N Z; McCoin, Colin S; Allen, Julie; Bell-Glenn, Shelby; Koestler, Devin C; Dorn, Gerald W; Thyfault, John P

Blood cytokine patterns suggest a modest inflammation phenotype in subjects with long-chain fatty acid oxidation disorders

血液细胞因子模式提示长链脂肪酸氧化障碍患者存在轻度炎症表型。

McCoin, Colin S; Gillingham, Melanie B; Knotts, Trina A; Vockley, Jerry; Ono-Moore, Kikumi D; Blackburn, Michael L; Norman, Jennifer E; Adams, Sean H

Unique plasma metabolomic signatures of individuals with inherited disorders of long-chain fatty acid oxidation

遗传性长链脂肪酸氧化障碍患者的独特血浆代谢组学特征

McCoin, Colin S; Piccolo, Brian D; Knotts, Trina A; Matern, Dietrich; Vockley, Jerry; Gillingham, Melanie B; Adams, Sean H

Acylcarnitines--old actors auditioning for new roles in metabolic physiology

酰基肉碱——代谢生理学领域中正在试镜的新角色

McCoin, Colin S; Knotts, Trina A; Adams, Sean H