McCole相关文献与解析，生知库 | 链接生命科学的每一步

A specific form of cPRC1 containing CBX4 is co-opted to mediate oncogenic gene repression in diffuse midline glioma

含有 CBX4 的特定形式的 cPRC1 被利用来介导弥漫性中线胶质瘤中的致癌基因抑制。

doi:10.1016/j.molcel.2025.04.026

Eimear Lagan ,Dáire Gannon ,Ademar Jesus Silva ,Peter Bibawi ,Anthony M Doherty ,Darragh Nimmo ,Rachel McCole ,Craig Monger ,Giovani Luiz Genesi ,Aurelie Vanderlinden ,James A Innes ,Charlotte L E Jones ,Lu Yang ,Bryan Chen ,Guido van Mierlo ,Pascal W T C Jansen ,Chinmayi Pednekar ,Alexander Von Kriegsheim ,Kieran Wynne ,Francisco J Sánchez-Rivera ,Yadira M Soto-Feliciano ,Angel M Carcaboso ,Michiel Vermeulen ,Giorgio Oliviero ,Chun-Wei Chen ,Richard E Phillips ,Adrian P Bracken ,Gerard L Brien

Intestinal epithelial PTPN2 limits pathobiont colonization by immune-directed antimicrobial responses

肠道上皮细胞PTPN2通过免疫介导的抗菌反应限制病原菌的定植。

期刊:Gut Microbes

影响因子:11

doi:10.1080/19490976.2025.2559029

Chatterjee, Pritha; Spalinger, Marianne R; Acevedo, Charly; Santos, Alina N; Gries, Casey M; Manz, Salomon M; Canale, Vinicius; Shawki, Ali; Sayoc-Becerra, Anica; Lei, Hillmin; Crawford, Meli'sa S; Eckmann, Lars; Borneman, James; McCole, Declan F

The PTPN2 rs1893217 IBD risk allele increases susceptibility to AIEC invasion by a JAK-STAT-CEACAM6 axis.

PTPN2 rs1893217 IBD 风险等位基因通过 JAK-STAT-CEACAM6 轴增加 AIEC 侵袭的易感性

期刊:Gut Microbes

影响因子:11

doi:10.1080/19490976.2025.2526136

Chatterjee Pritha, Canale Vinicius, King Stephanie J, Shawki Ali, Lei Hillmin, Santos Alina N, Haddad Michael, Gries Casey, McGovern Dermot P B, Borneman James, McCole Declan F

A conserved switch to less catalytically active Polycomb repressive complexes in non-dividing cells

在非分裂细胞中，一种保守的机制会将多梳抑制复合物的催化活性降低。

期刊:Cell Reports

影响因子:7.5

doi:10.1016/j.celrep.2024.115192

Rachel McCole ,James Nolan ,David M Reck ,Craig Monger ,Samantha Rustichelli ,Eric Conway ,Gerard L Brien ,Cheng Wang ,Orla Deevy ,Hannah K Neikes ,Frances M Bashore ,Aoibhinn Mooney ,Richard Flavin ,Elisabeth Vandenberghe ,Sarena F Flanigan ,Diego Pasini ,Chen Davidovich ,Michiel Vermeulen ,Lindsey I James ,Evan Healy ,Adrian P Bracken

细胞生物学

发表日期：2025

文献求助收藏

Tofacitinib Mitigates the Increased SARS-CoV-2 Infection Susceptibility Caused by an IBD Risk Variant in the PTPN2 Gene.

托法替尼可减轻由 PTPN2 基因中的 IBD 风险变异引起的 SARS-CoV-2 感染易感性增加

期刊:Cellular and Molecular Gastroenterology and Hepatology

影响因子:7.4

doi:10.1016/j.jcmgh.2024.101447

Spalinger Marianne R, Sanati Golshid, Chatterjee Pritha, Hai Rong, Li Jiang, Santos Alina N, Nordgren Tara M, Tremblay Michel L, Eckmann Lars, Hanson Elaine, Scharl Michael, Wu Xiwei, Boland Brigid S, McCole Declan F

新冠

发表日期：2025

文献求助收藏

Primary school-based food environment intervention increases diet diversity: Project Daire, a cluster randomized controlled trial

以小学为基础的食物环境干预措施可增加膳食多样性：Daire 项目，一项整群随机对照试验

期刊:International Journal of Behavioral Nutrition and Physical Activity

影响因子:5.5

doi:10.1186/s12966-025-01842-4

Olgacher, Dilara; Wallace, Ciara; Brennan, Sarah F; Lavelle, Fiona; Moore, Sarah E; McKinley, Michelle C; McCole, Patrick; Hunter, Ruth F; Dunne, Laura; Cardwell, Chris R; McCarthy, Danielle; Woodside, Jayne V

发表日期：2025

文献求助收藏

PTPN2 Regulates Iron Handling Protein Expression in Inflammatory Bowel Disease Patients and Prevents Iron Deficiency in Mice.

PTPN2 调节炎症性肠病患者体内铁处理蛋白的表达，并预防小鼠缺铁

期刊:International Journal of Molecular Sciences

影响因子:4.9

doi:10.3390/ijms26073356

Lei Hillmin, Shawki Ali, Santos Alina N, Canale Vinicius, Manz Salomon, Crawford Meli'sa S, Chatterjee Pritha, Spalinger Marianne R, Scharl Michael, McCole Declan F

Process evaluation of Project Daire: a food environment intervention that impacted food knowledge, wellbeing and dietary habits of primary school children

“戴尔项目”过程评估：一项影响小学生食品知识、健康和饮食习惯的食品环境干预措施

期刊:BMC Public Health

影响因子:3.6

doi:10.1186/s12889-025-21628-4

Anderson, Naomi; Brennan, Sarah F; Lavelle, Fiona; Moore, Sarah E; Olgacher, Dilara; Junkin, Amy; Dean, Moira; McKinley, Michelle C; McCole, Patrick; Hunter, Ruth F; Dunne, Laura; O'Connell, Niamh E; Elliott, Chris T; McCarthy, Danielle; Woodside, Jayne V

发表日期：2025

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Respiratory Exposure to Agriculture Dust Extract Alters Gut Commensal Species and Key Metabolites in Mice

呼吸道暴露于农业粉尘提取物会改变小鼠肠道共生菌群及其关键代谢物

期刊:Journal of Applied Toxicology

影响因子:2.8

doi:10.1002/jat.4808

Crawford, Meli'sa S; Ulu, Arzu; Ramirez, Briana M; Santos, Alina N; Chatterjee, Pritha; Canale, Vinicius; Manz, Salomon; Lei, Hillmin; Soriano, Sarah Mae; Nordgren, Tara M; McCole, Declan F

Goblet of fire: how Chlamydia ignites region-specific colitis by hijacking goblet cells

火之杯：衣原体如何通过劫持杯状细胞引发区域特异性结肠炎

A specific form of cPRC1 containing CBX4 is co-opted to mediate oncogenic gene repression in diffuse midline glioma

含有 CBX4 的特定形式的 cPRC1 被利用来介导弥漫性中线胶质瘤中的致癌基因抑制。

Intestinal epithelial PTPN2 limits pathobiont colonization by immune-directed antimicrobial responses

肠道上皮细胞PTPN2通过免疫介导的抗菌反应限制病原菌的定植。

The PTPN2 rs1893217 IBD risk allele increases susceptibility to AIEC invasion by a JAK-STAT-CEACAM6 axis.

PTPN2 rs1893217 IBD 风险等位基因通过 JAK-STAT-CEACAM6 轴增加 AIEC 侵袭的易感性

A conserved switch to less catalytically active Polycomb repressive complexes in non-dividing cells

在非分裂细胞中，一种保守的机制会将多梳抑制复合物的催化活性降低。

Tofacitinib Mitigates the Increased SARS-CoV-2 Infection Susceptibility Caused by an IBD Risk Variant in the PTPN2 Gene.

托法替尼可减轻由 PTPN2 基因中的 IBD 风险变异引起的 SARS-CoV-2 感染易感性增加

Primary school-based food environment intervention increases diet diversity: Project Daire, a cluster randomized controlled trial

以小学为基础的食物环境干预措施可增加膳食多样性：Daire 项目，一项整群随机对照试验

PTPN2 Regulates Iron Handling Protein Expression in Inflammatory Bowel Disease Patients and Prevents Iron Deficiency in Mice.

PTPN2 调节炎症性肠病患者体内铁处理蛋白的表达，并预防小鼠缺铁

Process evaluation of Project Daire: a food environment intervention that impacted food knowledge, wellbeing and dietary habits of primary school children

“戴尔项目”过程评估：一项影响小学生食品知识、健康和饮食习惯的食品环境干预措施

Respiratory Exposure to Agriculture Dust Extract Alters Gut Commensal Species and Key Metabolites in Mice

呼吸道暴露于农业粉尘提取物会改变小鼠肠道共生菌群及其关键代谢物